ID   A0A1A6HBE1_NEOLE        Unreviewed;       166 AA.
AC   A0A1A6HBE1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Prolactin {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=A6R68_17935 {ECO:0000313|EMBL:OBS75614.1};
OS   Neotoma lepida (Desert woodrat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Neotominae; Neotoma.
OX   NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS75614.1, ECO:0000313|Proteomes:UP000092124};
RN   [1] {ECO:0000313|EMBL:OBS75614.1, ECO:0000313|Proteomes:UP000092124}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=417 {ECO:0000313|EMBL:OBS75614.1};
RC   TISSUE=Liver {ECO:0000313|EMBL:OBS75614.1};
RA   Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT   "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT   lepida.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC       ECO:0000256|RuleBase:RU003618}.
CC   -!- SIMILARITY: Belongs to the somatotropin/prolactin family.
CC       {ECO:0000256|ARBA:ARBA00008474, ECO:0000256|RuleBase:RU003618}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS75614.1}.
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DR   EMBL; LZPO01036163; OBS75614.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A6HBE1; -.
DR   STRING; 56216.A0A1A6HBE1; -.
DR   Proteomes; UP000092124; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR001400; Somatotropin/Prolactin.
DR   PANTHER; PTHR11417:SF34; PROLACTIN-3C1; 1.
DR   PANTHER; PTHR11417; SOMATOTROPIN,PROLACTIN; 1.
DR   Pfam; PF00103; Hormone_1; 1.
DR   PRINTS; PR00836; SOMATOTROPIN.
DR   SUPFAM; SSF47266; 4-helical cytokines; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hormone {ECO:0000256|RuleBase:RU003618};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..166
FT                   /note="Prolactin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008346247"
FT   NON_TER         166
FT                   /evidence="ECO:0000313|EMBL:OBS75614.1"
SQ   SEQUENCE   166 AA;  19131 MW;  7D9494344C5578D0 CRC64;
     MGLLLLVSSL LPWDHVISTS DDQMSNEELY NKLISISHRT HIVARKMYKI LTEDLLKVII
     NVSNAWRYPL KLLTPAVLTH LGSYDGMLAR AVEVNYGSEA ILQGAKVLLS RVQPGFEENV
     YPDWPELKQL RSSNEDTHLS AFHTLFYCLH KDIQKVKRYL RILRGR
//