ID A0A1A6HBF3_NEOLE Unreviewed; 541 AA.
AC A0A1A6HBF3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A6R68_17660 {ECO:0000313|EMBL:OBS75888.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS75888.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS75888.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS75888.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS75888.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS75888.1}.
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DR EMBL; LZPO01035187; OBS75888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6HBF3; -.
DR STRING; 56216.A0A1A6HBF3; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16756; RING-HC_TRIM36_C-I; 1.
DR CDD; cd12894; SPRY_PRY_TRIM36; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR040859; Midline-1_COS.
DR InterPro; IPR035727; SPRY/PRY_TRIM36.
DR InterPro; IPR027726; Trim36_HC-RING.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24099:SF18; E3 UBIQUITIN-PROTEIN LIGASE TRIM36; 1.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR Pfam; PF18568; COS; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 33..84
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 209..266
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 309..533
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 419..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 61615 MW; D2F7D21EF191F9EE CRC64;
MSESGETSEF GYIMELLAKG KVTIKNIEKE LICPACKELF THPLILPCQH SICHKCVKEL
LLSLDDSFND VASDNSNQSS PRLRLTSPSM DKIDKISRPE LLSKKRLMRV EKLSKDIDFL
IGKEGQVKSQ ISELNLLMKE TECNGERAKE EALAHFEKLF EILEDKKSSV LKAIDASKKL
RLDKFHMQVE EYQGLLENNG LVGYAQEVLK ETDQSCFVQT AKQLHLRIQK ATESLKSFRP
AAQASFEDYV VNTSKQTEVL GELSFFSSGI DIPEINEEQS KVYNNALINW HQPEKDKADS
YVLEYRKINR DEEMMSWSEL EVHGTIFSFL FDEKCGYNNE HLLLNLKRDR VESRAGFNVL
LAAERIQVGY YTSLDYIIGD VGITKGKHFW ACRVEPYSYL VKVGVASSDK LQEWLRSPRD
AASPRYEQDS GHDSGSEEAC FDSSQPFTLV TIGMKKFFIP KSPTSNEPEN RVLPMPTSIG
IFLDCDKGKV SFYDMDHMKC LYERQVDCSH TMYPAFALMG SGGIQLEEPI TAKYLEYEEA
V
//
