ID A0A1A6HEM4_NEOLE Unreviewed; 818 AA.
AC A0A1A6HEM4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
DE Flags: Fragment;
GN ORFNames=A6R68_16845 {ECO:0000313|EMBL:OBS76706.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS76706.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS76706.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS76706.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS76706.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NLRP family.
CC {ECO:0000256|ARBA:ARBA00008665}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS76706.1}.
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DR EMBL; LZPO01034877; OBS76706.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6HEM4; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR PANTHER; PTHR45690:SF7; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 5; 1.
DR Pfam; PF13516; LRR_6; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM00368; LRR_RI; 9.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 17..147
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT NON_TER 818
FT /evidence="ECO:0000313|EMBL:OBS76706.1"
SQ SEQUENCE 818 AA; 93114 MW; 11B9DDBE4ED698A7 CRC64;
MRVLFEAFKP HQKISPHTVI LHGRPGVGKS VLARSIILGW AQDKLYQDVS YAFLFXAGEI
KWTEKSSLAQ LISREWPDSP APMTEIMSKP ERLLFVMDGF DDLDSALLHD DMRLSEEWED
ERPIYVLMYS LLMKALLPES FVVITTRDIG LEKLKSLVVS PLYILVEGLS ATRRTGLVLK
AISDSHQRNQ VIHSVIDNHQ LFDECQVPSI CSLICEALQL QENLGDRGPP VCQTFTGLYA
TLMLYQLIPI DPSRSCLNRE ERVALLGLCR MAAEGVWNMR SVFYEDDLQT HGLRESEISA
LFHMNNILLR VDHSTEWCYV FFHLSLQDFC AALYYVLEGL GERDQHSFFI KNPRSFMELK
QTDFNTHLLG MKRFLFGLMN KDTMMNLEVL LGCPIFPTVR QKLQRWVFVL GQQVSATSPM
DVLDAFHYLF ESQDEEFVRW ALNSFQEVYL LLNQKMDLMV SSYCLQHCQN LKTLRVDVRD
IFSVDKNTEL CPIVPQQTQS KPLIMERWEN FCYVLSTHQK LKQLDLGSSV LNEWAMKILC
LKLRNPACNV QILTNRNLKY LNLGNTLMRD DDVKLACEAL KHPNCSLETL RLDSCELTPE
CYPVISNLLL STTSLKSLSL ARNKVVEKSM RLLCEALSSS KCALQKLILD SCELTPVSCQ
VLASALLNNH TLTHLCLSNN QLRTEEVREL CQFMRHPECA LQRLILVGCQ LTEDCCEDLA
CMITANKHLK SLDLSHNALG DTGVIALCKG LKHSDCSLRR LGLEACGLTS KCCEVLSSAL
SYNQHLTSLN LIKNDFGTSG MLKLCSAFLH PTSNLWRI
//
