ID A0A1A6HLQ9_NEOLE Unreviewed; 764 AA.
AC A0A1A6HLQ9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Aryl hydrocarbon receptor nuclear translocator {ECO:0000256|ARBA:ARBA00039652};
GN ORFNames=A6R68_18426 {ECO:0000313|EMBL:OBS79231.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS79231.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS79231.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS79231.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS79231.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS79231.1}.
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DR EMBL; LZPO01027203; OBS79231.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6HLQ9; -.
DR STRING; 56216.A0A1A6HLQ9; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd18947; bHLH-PAS_ARNT; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF50; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 65..118
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 137..211
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 337..388
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 36..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..753
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 84230 MW; F250E29170CDA9B1 CRC64;
MTSDVPSLGP TIASGNPGPG IQGGGAVVQR AIKRRSGCDD EQMCSDKERF ARSDDEQSSA
DKERLARENH SEIERRRRNK MTAYITELSD MVPTCSALAR KPDKLTILRM AVSHMKSLRG
TGNTSTDGSY KPSFLTDQEL KHLILEAADG FLFIVSCETG RVVYVSDSVT PVLNQPQSEW
FGSTLYDQVH PDDVDKLREQ LSTSENALTG RILDLKTGTV KKEGQQSSMR MCMGSRRSFI
CRMRCGNSSV DPVSMNRLSF LRNRCRNGLG SVKEGEPHFV VVHCTGYIKA WPPAGVSLPD
DDPEAGQGSK FCLVTSSPNC TDMSNICQPT EFISRHNIEG IFTFVDHRCV ATVGYQPQEL
LGKNIVEFCH PEDQQLLRDS FQQVVKLKGQ VLSVMFRFRS KNREWLWMRT SSFTFQNPYS
DEIEYIICTN TNVKNSSQEP RPTLSNTIQR SQLGPTTNLS LEMGTGQLAS RQQQQQQQQQ
QQTELDMVPG RDGLASYNHS QVSVQPVATT GAEHSKPLEK SDGLFAQDRD PRFSEIYPNI
SADQSKGISS STVPATQQLF SQGNSFPPNP RPAENFRNSG LTPPVTIVQP SSSAGQMLAQ
ISRHSNPTQG AAPTWTPSTR PGFSAQVPTQ ATAKTRSSQF GVSNFQTSSS FSAMSLPGAP
TGSQGTAAYP TLTNRGSNFP PETGQTAGQF QTRTAEGVGV WPQWQGQQPH HRSSSNEQHV
QQTSAQPPSQ PEVFQEMLSM LGDQSNSYNN EEFPDLTMFP PFSE
//
