ID A0A1A6HRN1_NEOLE Unreviewed; 316 AA.
AC A0A1A6HRN1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=A6R68_21126 {ECO:0000313|EMBL:OBS80670.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS80670.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS80670.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS80670.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS80670.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS80670.1}.
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DR EMBL; LZPO01017326; OBS80670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6HRN1; -.
DR STRING; 56216.A0A1A6HRN1; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04387; RhoGAP_Bcr; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037769; Abr/Bcr.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23182:SF5; ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN; 1.
DR PANTHER; PTHR23182; BREAKPOINT CLUSTER REGION PROTEIN BCR; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 104..302
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 316 AA; 35876 MW; 38E7C0C3EAFE299B CRC64;
MTDILPQPDC SLKAVCESLE HCCLDQLEEP GSKRVPNTGA RLWGRVRSKL LRHKLDPQTV
ETKNWHTDVI EMNGIKVEFS MKFTSRDMSL KRTPSKKQTG VFGVKISVVT KRERSKVPYI
VRQCVEEVEK RGIEEVGIYR ISGVATDIQA LKAVFDANNK DILLMLSDMD INAIAGTLKL
YFRELPEPLL TDRLYPAFME GIALSDPAAK ENCMMHLLRS LPDPNLITFL FLLEHLKRVA
EKEPINKMSL HNLATVFGPT LLRPSEVESK AHLTSAADIW SHDVMAQVQV LLYYLQHPPI
SFAELKRNTL YFSTDV
//
