ID A0A1A6HSB6_NEOLE Unreviewed; 571 AA.
AC A0A1A6HSB6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
DE Flags: Fragment;
GN ORFNames=A6R68_20455 {ECO:0000313|EMBL:OBS81353.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS81353.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS81353.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS81353.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS81353.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS81353.1}.
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DR EMBL; LZPO01017281; OBS81353.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6HSB6; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd01475; vWA_Matrilin; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 19..198
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 371..546
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OBS81353.1"
FT NON_TER 571
FT /evidence="ECO:0000313|EMBL:OBS81353.1"
SQ SEQUENCE 571 AA; 62990 MW; BF0F3D84EC520431 CRC64;
PWESQLQSAG PRCYTGPLDL VFVIDSSRSV RPFEFETMRQ FLVGLLRSLD VGLNATRVGV
IQYSSQVQSV FPLGAFSRRE DMERAIRAVV PLAQGTMTGL AIQYAMNVAF SEAEGARPPE
ERVPRVLVIV TDGRPQDRVA EVAAQARARG IEIYAVGVQR ADVGSLRAMA SPPLDQHVFL
VESFDLIQEF GLQFQGRLCG KDLCAEWGHG CQHQCVNAPG TFYCTCNSGY RLAPDNKSCL
AMDLCAEGTH GCEHICVNSL DSYFCRCRAG FALQQDQRSC RAIDYCSFGN HSCQHECVST
LVGPQCRCRE GHDLLPDGRN CXVKDFCNGV DHGCEFQCVS EGLSFRCLCP EGRRLQADGK
SCDRCREGHV DLVLLVDGSK SVRPQNFELV KRFVNQIVDF LDVSPEGTRV GLVQFSSRVR
TEFPLGRYGT AAEVKQAVLA VEYMERGTMT GLALRHMVEH SFSEAQGARP RDLNVPRVGL
VFTDGRSQDD ISVWAARAKE EGIVMYAVGV GKAVEEELRE IASEPWELHV SYSPDFSTMT
HLLENLKGSI CPEEGIGAGT ELRSPCECES L
//
