ID A0A1A6HSU5_NEOLE Unreviewed; 520 AA.
AC A0A1A6HSU5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN ORFNames=A6R68_20710 {ECO:0000313|EMBL:OBS81075.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS81075.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS81075.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS81075.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS81075.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS81075.1}.
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DR EMBL; LZPO01017293; OBS81075.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6HSU5; -.
DR STRING; 56216.A0A1A6HSU5; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF52; KERATIN, TYPE II CUTICULAR HB6; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 104..415
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 492..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..247
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 313..393
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 520 AA; 58512 MW; 057A0F3AFFD2E7C6 CRC64;
MTCGFPTGNF SCASACGPRP GRCCISAAPY RGISCYRGLS GGFGSHSVCG AFRSGSCGRS
FGYRSGGVCG PTPPCITTVS VNESLLTPLN LEIDPNAQCV KHEEKEQIKC LNSKFAAFID
KVRFLEQQNK LLETKWQFYQ NRKCCESNVE PLFEGYIETL RREAECVEAD SGRLAAELNH
AQEAMEGYKK RYEEEVALRA TAENEFVALK KDVDCAYLRK SDLEANAEAL TQEIDFLRRL
YEEETRILHA HISDTSVIVK MDNSRDLNMD CIVAEIKAQY DDIATRSRAE AESWYRTKCE
EMKATVIRHG ETLRRTREEI NELNRVIQRL TAEIENAKCQ NTKLEAAVTQ SEQQGEAALT
DARCKLTELE AALQKAKQDM ACLLKEYQEV MNSKLGLDIE IATYRRLLEG EEQRCQQLPW
WSCVRGPVCV WLTASDRQCL QCPMQWECGS EHWPVCALWK RLLLPGEVLG VKREPGSGLP
HRAEHSSLKV SWSPSLASPW GPRMPSTPGK YRDKSSVGLL
//
