ID A0A1A6HTS8_NEOLE Unreviewed; 624 AA.
AC A0A1A6HTS8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 08-NOV-2023, entry version 28.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=A6R68_20428 {ECO:0000313|EMBL:OBS81400.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS81400.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS81400.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS81400.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS81400.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS81400.1}.
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DR EMBL; LZPO01017280; OBS81400.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6HTS8; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16450; mRING-C3HGC3_RFWD3; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037381; RFWD3.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16047:SF7; E3 UBIQUITIN-PROTEIN LIGASE RFWD3; 1.
DR PANTHER; PTHR16047; RFWD3 PROTEIN; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 185..229
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 258..308
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 100..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 69097 MW; 944370DF1E94B236 CRC64;
METANPGTSE EHRQGSGANQ TIRAATAVSM NNFISGLQRL HNMLEMLRPP PSGHSVGPVR
MRRRVGSVLR ARTGGSQRPD GARLRTPVYA YFQVSRSQPY VSATAPDSET RNQTSGTDSD
SDSSAENEEV VVQTEEPEAN VPEGGVTSTE QEATSVTGGD AVPGTQSLQK PNVLPSVDDE
EGETCTICFE QWTSAGDHRL SALRCGHLFG YRCISKWLKG QTRKCPQCNK KAKHSDIVVL
YARSLRALDT NEQERIKSDL LNEQMLRKQA ELESAQCRLQ LQVLIDKCTK LNSRVQDLET
VVMRHQNEVK QQPRGSQALG WNCLPSSQNQ HKYHFQKTFT VSQTGNCRIM AYSDGLSCLV
VSQPSPQSSF IPGFGVKMLS TANMKSSQYI PMHGKQIRGL AFSSXSKGLL LSASFDNTIK
LTSLETNTVV QTYNTGRPVW SCCWCLDENN YIYAGLANGS ILIYDLRNTN AYIQELVPQK
ARCPLVSLSY LPRAAVAAFP YGGVLAGTLE NASFWELKTD FSHKPHVLSL EPGGFVDFQT
ESSTRHCLVT YRPDKSHNTI RTVLLEMSYK LDDAGEPLWN GGSGLLLQDL KTDQPVLDIC
PFEANQNSYL ATLTEKAVNF YKWE
//
