ID A0A1A8T527_9GAMM Unreviewed; 395 AA.
AC A0A1A8T527;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Multidrug export protein EmrA {ECO:0000313|EMBL:SBS27414.1};
GN Name=emrA_1 {ECO:0000313|EMBL:SBS27414.1};
GN ORFNames=MSP8886_00841 {ECO:0000313|EMBL:SBS27414.1};
OS Marinomonas spartinae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=1792290 {ECO:0000313|EMBL:SBS27414.1, ECO:0000313|Proteomes:UP000092544};
RN [1] {ECO:0000313|EMBL:SBS27414.1, ECO:0000313|Proteomes:UP000092544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8886 {ECO:0000313|EMBL:SBS27414.1,
RC ECO:0000313|Proteomes:UP000092544};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FLOB01000002; SBS27414.1; -; Genomic_DNA.
DR RefSeq; WP_067014414.1; NZ_FLOE01000005.1.
DR AlphaFoldDB; A0A1A8T527; -.
DR STRING; 1792290.MSP8886_00841; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000092544; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092544};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 19..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 55..285
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 286..341
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 155..182
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 395 AA; 43329 MW; AA4D20FB08A5A0B9 CRC64;
MQDNDNTVTP KKSQRKKSLM IFLGIIILGA IGVGGYYEEF VVGNTTTDDA YVKGNIVSIT
PETVGTVTEI AADNGDFVKK GQVLVRFDQT DADLQFENAK AQLAQAVRKV RAMFNNVTQA
EAVVEANKIA LHKAQRDYDR RKNMVKAGGL SQEDLSHAKD MVESAQTQLN VAEEQLKAQS
SMISGTTVET HPIVLSAISA LKQAYLAKQR TSIVAPVTGY VARRQVQLGQ RVSPNSTLMA
VVPLNEVWVD ANFKETQLDN MRIGQPVKLV SDLYGDKVVY HGTVESLGIG TGSAFSVLPA
QNATGNWIKI VQRLPVRIKL DTNDLAAHPL RIGLSMNVDV DTVTQTGKLL STSSPKKPRY
ETNVYQKQME NIQQIVSRII KDNDPQLNHA PKNKS
//
