ID A0A1A8TCZ6_9GAMM Unreviewed; 951 AA.
AC A0A1A8TCZ6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cyclic di-GMP phosphodiesterase Gmr {ECO:0000313|EMBL:SBS30644.1};
DE EC=3.1.4.52 {ECO:0000313|EMBL:SBS30644.1};
GN Name=gmr_9 {ECO:0000313|EMBL:SBS30644.1};
GN ORFNames=MAQ5080_01733 {ECO:0000313|EMBL:SBS30644.1};
OS Marinomonas aquimarina.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=295068 {ECO:0000313|EMBL:SBS30644.1, ECO:0000313|Proteomes:UP000092627};
RN [1] {ECO:0000313|EMBL:SBS30644.1, ECO:0000313|Proteomes:UP000092627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5080 {ECO:0000313|EMBL:SBS30644.1,
RC ECO:0000313|Proteomes:UP000092627};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FLOC01000008; SBS30644.1; -; Genomic_DNA.
DR RefSeq; WP_067208594.1; NZ_LTAV01000009.1.
DR AlphaFoldDB; A0A1A8TCZ6; -.
DR STRING; 295068.MAQ5080_01733; -.
DR OrthoDB; 9176779at2; -.
DR Proteomes; UP000092627; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071111; F:cyclic-guanylate-specific phosphodiesterase activity; IEA:UniProtKB-EC.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:SBS30644.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092627};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..329
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 333..386
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 383..429
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 456..508
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 540..674
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 683..937
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 951 AA; 107922 MW; 842CE13902C56511 CRC64;
MSLQSSSKKK SLFTVVSSAI MLLVSLVFIA NSFYFYKIQK EQLELEIIGQ AEESAGRLSQ
TLASFMESYQ INEYQKLVQS EILTPNHYAL SAILVEDFNM AEIVGEEHFV TGRIIDAAGN
SRPYSSTQPE DQALLENAYH SKATEIRSSN GELIGRLFVY VGARTLERSI EALVVNTAVI
TVALLFLLLT LLYFLLQKLL IYPLSHFTQV IADCNEDGIP RAPMPESNYR EIDDLSNTVR
DMVNAITIAQ DRLKQERLEL ENVINGTRTG TWYWNIPTGQ TRFNERWASM VGYTLEELHP
ISIDTWVSLA HPEDAKLSEK ALKAYFNGET DYYECEARMR HKDGHWVWVL DRGQVFQWND
QGEPIDMFGT HQDITVRKQS EVELALAASV YQQVHEGILI SNVAGQIVDV NDAFTRITGY
QRDEVIGQQP SILKSGRHDK SFYDQLWQTL KTEGCWSGEV WNKRKNGDIY PELITISAVT
DSFGELSHYV ALFSDITSLK EHEYQLERIA HYDSLTGLPN RFLFRDRLRV AMSRAKSRNE
KLALLFLDLD GFKEVNDSFG HEVGDQLLVY LATTITSLLR REDTFARIGG DEFILILPDA
TKDNVLEKVI HTLLESIAEP VDLNGRLVQV TSSIGVAIYP ENDDMDADQL IRQADQAMYS
AKVAGKNLCR FFDPEQDRSI RGFHENVTRL SEALAADEFE LYYQPKVNLR SLEVVGFEAL
IRWHHPEQGV LLPGRFLPDI EGNLLMVEIG EWTIRQALEQ LFIWQQHGLH LPISVNVSAI
HLQQKNFIDS LEEVLIEYPT VPPKYLEFEV LETSALENME QAQLIIHHCD DLGIEFSIDD
FGTGYSSLSY LRDIPAKTLK IDQSFVKNMS DENDDRLILE GIIGLAKSFH KKVIAEGVED
MAYADVLLEL GCEYAQGYAI ARPMPAADVP QWVAQWRAQT ISQQASAPGL L
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