ID A0A1A8VUY3_PLAMA Unreviewed; 545 AA.
AC A0A1A8VUY3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=RhoGAP GTPase, putative {ECO:0000313|EMBL:SBS84299.1};
GN Name=PmUG01_08023000 {ECO:0000313|EMBL:SCN12105.1};
GN ORFNames=PMALA_009360 {ECO:0000313|EMBL:SBS84299.1}, PMUG01_08023000
GN {ECO:0000313|EMBL:SCN12105.1};
OS Plasmodium malariae.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5858 {ECO:0000313|EMBL:SBS84299.1, ECO:0000313|Proteomes:UP000078597};
RN [1] {ECO:0000313|Proteomes:UP000078597}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Naeem Raeece;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SBS84299.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SCN12105.1, ECO:0000313|Proteomes:UP000219813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FLQW01000506; SBS84299.1; -; Genomic_DNA.
DR EMBL; LT594629; SCN12105.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A8VUY3; -.
DR VEuPathDB; PlasmoDB:PmUG01_08023000; -.
DR OMA; PTRVREY; -.
DR OrthoDB; 3030820at2759; -.
DR Proteomes; UP000078597; Unassembled WGS sequence.
DR Proteomes; UP000219813; Chromosome 8.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000219813}.
FT DOMAIN 195..388
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 390..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..504
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 62468 MW; 6C183213051D17EF CRC64;
MLDSDAEVPQ EILVEYEKLL KKSYTENFDE LYKTDLLKVI GKDGYGSHIV LLIPCFIISS
GADPEKTLRY AIMTLDPVVK ENYVLILCET HTNWLNDAVY TYAKQWYDTL PRKYKKNLKR
LYLVHSGFLS KTVLTIITPF VSAKFWKKVE YIEKLEDLFL KLNVNPTIFL RHFPYIVQRN
EEVLLGEKPV SVFGSDLEIL CQRFGKGYKE FKYIPSIVVD FLSHLTKTEI INTKDLFYLQ
TDANSLYGIV GDIEYGEPTT DFNNIPSLVC SFRLFLDTQK HGLLGKDAFS RLYHLKIVSA
SDKVIRANLF KLYNKLEQGV KECLLCLLKF FKTVSIHSSE NNMTIETLAK IFSSTFFRPR
IPNAVFSECI PLANKCLQML IETPEILTNP QIYDTDSDSS EMSEGDSELE ESKEKEEISD
SSSNEEEGEE KEEGEESEHS SSEGERDSDK SALLNTSLNS GDEEKVEDKE KKKKSELKNE
ILDGNSDEGS EDDESEEDSM EDTVEDTGEQ SKDESKDESK DESKNKLNSG KNSKRVNFKR
EELKE
//
