ID A0A1A8W6C3_9APIC Unreviewed; 2992 AA.
AC A0A1A8W6C3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Rap guanine nucleotide exchange factor, putative (EPAC) {ECO:0000313|EMBL:SBS87551.1};
GN ORFNames=POVCU2_0043280 {ECO:0000313|EMBL:SBS87551.1};
OS Plasmodium ovale curtisi.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=864141 {ECO:0000313|EMBL:SBS87551.1, ECO:0000313|Proteomes:UP000078560};
RN [1] {ECO:0000313|Proteomes:UP000078560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Naeem Raeece;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FLQU01000580; SBS87551.1; -; Genomic_DNA.
DR Proteomes; UP000078560; Unassembled WGS sequence.
DR CDD; cd00038; CAP_ED; 4.
DR Gene3D; 2.60.120.10; Jelly Rolls; 5.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR PANTHER; PTHR11635:SF152; CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SUBUNIT; 1.
DR Pfam; PF00027; cNMP_binding; 3.
DR SMART; SM00100; cNMP; 4.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 5.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 5.
PE 4: Predicted;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000078560}.
FT DOMAIN 1527..1628
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 1814..1909
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 1949..2074
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 2588..2689
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 2715..2819
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 245..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2154..2175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2263..2320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2895..2992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2284..2320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2895..2909
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2910..2934
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2945..2976
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2977..2992
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2992 AA; 351705 MW; 150704E5D2EF8B7C CRC64;
MYLQNISPED LDDYMKDEVL YLKIKELIRK RKRELDRMLD SNLNVLSNER NNIERRNYGN
LKLKLINNQE MLNEFSRNTK NNISLYNLNI HKKDNNFTYY INNKIFSQYM RYKQMYDIYM
QDKETYNKKI KKKEFNNFFY KHALHFKNDN VSQCNYNLCS NDLRNISVDL LKNAKNSKGL
FKKRDKCLPK NEAKEKRKNE HYIVDSAQKN NRTVEFVNTE EKDKMEKRKE GEIREREEME
MAIKEEKKRK LEKEKENKRD MEMEMEKEKE KEKEKEKENK RDMEMEMAIK EEKKRKLEKE
KENKREMEMA MEKGKEKGKE KGKEKGKEKG KEKGKEKGKE KEKKREKKKE KENERVKKKG
IREEKGAVSK SVCKNNLGEG YETTADISTI RDEVEENSHR MGYDEYMFEN KEKHDEPDMN
EKHNLNHFAY GDEPLEKFYA NVEHPRRHDS SLEVLRVNIK NLIKKKTEKN GNGNFETMKE
NLLNGQNLFI SVDEINKKNS IIHCDKRDNN ISDEMEEKPR QSSENSVISH KSVSVELIEE
DNEHTNTKKQ EVRRSEKRRD IKRKGLEEIK LDDNKGGKEK EKKKEYLNFF NEPKRVNDTE
SESGLNISDV EEGVANEYVE SGNNSLISHK LSSKSTEKNV NNALSMEEAE ETQEVENTEE
TQEVRHTEET QEVKHTEETQ EVKHTEETQE VKHTEETQEV KHTEETQEEK HTEDKRKETV
EESRPDKVDS LSDNSFNVKD REEQIFTYEN DNSYENKIMK SGSEFSDQDL FDNSKYSKVK
IHQFRKIIYH YDKNIFTFFT NLLLHSNINL VGKYQNRIFN VQIEATDMFQ YLVSKYTQPC
KSSKIDIEKK KKTNSESLYL NESEYKIVNE YICNNSSTSS LKMLYHKIHF IANQNYEEFK
NRLLEGGVIN LINLFHDEDI NNFDKIFDVS FVNFCDIVGI STDSCLYHFN CIDKNYKGKR
YIYLKHILQY LDVEKDMKEE YHKYNFISMH KKNLMYINIS ENFDNLNKFY KAVRKKNKLY
ISMNEFIYFF SEDEKMKKYN FSHDDIVSLY YSIVFYVYYT NKNKILQSLH FLSDNRFVYP
NGDGDNTKKI RHYVGGEIKL KQEKKENHNS GLTSDDGYNY VNYNLSLYKE YFTLDDFNFV
IELKDIYFYF EGSECPFSKI KRRIIEIYGS VKKGILINRE ICNVGNDNDE DANSSASDVE
TKNFDLGLDV DSFKLFMSDR YRYRHQERIS YYERHSSLTR RGTKVGKIGK VSKSWKSGKP
GKETKGDDEI GACKIDRKTF MCLMYNIGIH INHCLTLWDN FLPFLECDML DYKIFTGFLN
GKINISNNET EDSINIIKNN ILKTSEEKDM EFTRDYKNRL GGTICSRQFH DLKEIKSTHA
LTVDEIEVAA QILSIVCPFN FLSKNEKKDF VQKLKKTCYK KGYDFVSFSE CYLQSEDEND
GKDNKRYIDK KVIILLNGIL RNSKDSNFFI NSVNAVERDI LCNYVAHTNV AVIEVDDTLC
SDEFIKLVEK KKEISEEFMK IIDNIPIFKN FPYALKNSIS VNIQKCQFEK KKIIIRQHDD
PSNFYILKEG KINVYCNSVD TPINTISDCT FFGELSLIFN TLRTCDIIVE SDVAFCYSFS
KEYFLSLLNQ DVVKEFIKYF HANYRKEGIQ HIIANYANGK KRALTFDQDT NRNKQLEEAK
GDVPKMTNGI SEDGIGNTWI GSKRLSKGFS GLNELSDIHK LNSLRRESPV GSINKEFSSG
ILSTDNIILD VEYINQNNIN SFYSDLDKII LNIFNAEKKY FVEEMETHLM KVKTFEKIIK
KMKNKEQFLK NLLYEKCPKG KQIILEGDPC EYFYFVKKGE ISIQQFNQFK NMYEEIAIFG
DYTYFGHQLI LNKMKYFFIA LAKTDSELYK LDSHMFEKFL SPFIDILSKS NDINQIDTLT
EVINKDVQKK KKEENFIIKV MKILKKVSVI QKLTDEELYN GAKHFDFKFV KKGKIIIEYE
DTPDFFYIVK KGVVSVKMDN KEHDMEKDKE NNLNINTQED KVHTKKNNTI KCTYLYKYDY
FGELSIINNQ PRTATCEAHT NCFLLAIDKI SFSKNFSTIF NDLLQEADIR YTKHYSLPPW
LKSMYGNEIQ DNMRSISIKI PELDSCSSIS DESSEVFSFE EEIKKKLKVE KRKKGKIASA
DGEENGAPIG ESSDVRSQGS LTISINEKKL SEIKAEKNQK IEEIKRKELK VFERIKLKEE
KKIKAFMKKK GVVFPNCVNT TNDQPAHEEA PVDSVPNDAY LEMEQISSKR DKVVKKREKL
KKENKHSKPA GVDEQKRDTT DRSSETTKRN ANEDERRNSM IRTIPQKSLS ILKKKISTSS
SSEFNFDKLV KKLIDFIDSE YNSIFHFYES IDKFNTGYIK YNDFLSCIIS WNMEELFEGQ
ENLENLFKYL CDGKNILTLV DFYRNVYKGK DIDIFELNLR LSEVYGNTVS AFRKNIGLFN
VDNCICNYTN FETVCEKVGV SKANIKNIWD EINITNEENI PLEIIITTLN GELSIEESFN
AYNNKKSLLN QVVHFFQGNE DLTKMSTDIM ENNFEINYEE PIIINKQHHK IYPKECIYIV
QLLESNIHFK YLTIEQRKFF TTLMNRQVLK IDNIAIKQND EEGPIIFIYE GKANIITYNI
FGIETVIREL ENEEIYGCNE VINELPADYE VKISSDNAIV WILDRSVYKD NIKSMLEERK
NNCIHILPVL RNVPILRYLP EELLHNISYA MKVEFHEPNH TIIKANTYDD KYYIICKGLA
TVEKYSEIHK NKLILSILKK ADYFGELALI KNIKRTANVI LDTPTILLSL VDSEFNRLFS
SHFDKFLNRA KANYKKNEIE NKIVSIPLIN LTSTNNIGHA TYNRSKNKKV TIQDNGYAKS
VTRDLQNEIE VGVSSYQPAG NSDALQESTQ DSASEKKEEV SRKVYKELYP GDDIDPGEIA
KQGNSEKSNS EKNDVPHKHK ERKGEKEKVK NQVKEKKKER STHKKRDGKK KK
//
