ID A0A1A8WB64_PLAMA Unreviewed; 1418 AA.
AC A0A1A8WB64;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Metalloendopeptidase {ECO:0000313|EMBL:SBS88981.1};
GN ORFNames=PMALA_024490 {ECO:0000313|EMBL:SBS88981.1};
OS Plasmodium malariae.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5858 {ECO:0000313|EMBL:SBS88981.1, ECO:0000313|Proteomes:UP000078597};
RN [1] {ECO:0000313|Proteomes:UP000078597}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Naeem Raeece;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
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DR EMBL; FLQW01001308; SBS88981.1; -; Genomic_DNA.
DR VEuPathDB; PlasmoDB:PmUG01_12076800; -.
DR OMA; VEIHCSN; -.
DR Proteomes; UP000078597; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 2.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 82..141
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 262..314
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT DOMAIN 1246..1331
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 1418 AA; 168710 MW; 16A99069D9A9DE47 CRC64;
MEIKEYIHLV IIMGELHEDE DLIRYELPNR LTSIIYKKRK NTKRKRYILH NENHIILPSN
KISEEYKSCT NPIDYNYEEL HVYMEVNTGS INEKKNQQGI SHLCEHVSYM GSKNRKNIID
KNIRTNAYTD FHHVVFYISI SLNNEIYKEN SFSNFAHDGF IKNINEEEIE NFDIYSVDEF
NYKHTILSQC IETMIEVLKG ETQFNKERII KEKKAIFSEY SIINTVEYKM NSDIIKTLHK
ENRLSHRLPI GKLELLKRYD EKDIKQYFDL FFRPENVNLF VYGDINVDIA QKLINKKFEN
IKGKDLTRDE TAYLNILNEN TLKSRNKNLP AVVHAFGSNS SKGYEANGYS PERNDDSCTS
VVDERNNEYI DDNIIDSEKL KELKKKNQNE IMSELQFRSY LEDKYAVNLE EEKTLNRRDI
KNITTDVRIF KYSLNNVNIN ILLKEEIKSI TTLEDYKISI MKDIIFYCLS FRFNIHRNDL
FNSIDINEYT NINEGATIRT IEIKTTIKSF EKTINAFYTF IKSLRMYGLS NDELRNYKIN
EIECDEEEEA NKHGTTKNMK LIHPEKNEDE EYILDTKINE TYTDEIQKII DYNSCKHVYI
NEKREKKIKK KIFDNLKIEE INVYAKQYFE YIFNIFSEGT NFKPNCIIIH VPYNHFDTYN
KKDIKKLFFD NIYSKEQIPN LSLNIQSKLL SPQYIYENIT KKLRIAKYVQ PRTTSTKISV
FNYILNKINK IKKDYEHICP LQNLNTVPNF ALFKICYNVE IDKNHIEETN TEVQKKNDVK
WDYLKKEETY HMYEMHEMCK QNGKDTKEQS VKQGNYEKMQ SVQDKNIKDN GNILNLKKYI
LSNKGQKQVE NYELMNGIKV NLFKTNIDKK YIYLRLIIPH MDILKTKKYN VFLLLFSVIC
LFEGGEIENV GREHVEIHCS NRSINIYIDL NDEYFFIDIC TYNKYENINS AFSILNNILL
QTKVEQSALL RVVDKLKKDF FEYKNNLQVM LNCLIKPRSF LLGQTISYLS DGAIGYQNFN
LKETENISLE TVQHKLRELF RDLSLFEITI VGDISPFIHY YILHFLGTLQ GGKKINTEKG
ISTDTREHIR TNATIDVETD ENFTSKNYRT SNCITLPISS DEENDLRYEY NLLCPLKNFE
AKSKEITYVY LNEKEEHAVF LLIGKSANYF GFLSNGIHIS FYLLQFLKKM LFQFPQTNGK
KEEEKKALTT EFDKIKGHLN IKQYTEENLN EFFKKRRKLY TNPLFFNVVS YIIQYILNSK
FFHYLREKKE LTYDSSFEFL NYEKYFTGFF TLLVQTNPKD LQLIKKEVLS CFEDFTKNFY
NFSDYLIENA KLSYLNKKNK DLKYFVDKIS GMQLKDFPLK YRNKFLLKDN LILNKIEKID
ILLVLYVLFN QTQSYHISYG ISSPEDVWKV MYKNINKI
//
