ID   A0A1A8WFX9_PLAMA        Unreviewed;       247 AA.
AC   A0A1A8WFX9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Proliferating cell nuclear antigen {ECO:0000256|RuleBase:RU000641};
GN   ORFNames=PMALA_031470 {ECO:0000313|EMBL:SBS90978.1};
OS   Plasmodium malariae.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5858 {ECO:0000313|EMBL:SBS90978.1, ECO:0000313|Proteomes:UP000078597};
RN   [1] {ECO:0000313|Proteomes:UP000078597}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Naeem Raeece;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC       and is involved in the control of eukaryotic DNA replication by
CC       increasing the polymerase's processibility during elongation of the
CC       leading strand. {ECO:0000256|RuleBase:RU000641}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000641}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000256|ARBA:ARBA00010462,
CC       ECO:0000256|RuleBase:RU003671}.
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DR   EMBL; FLQW01001687; SBS90978.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A8WFX9; -.
DR   VEuPathDB; PlasmoDB:PmUG01_14060900; -.
DR   OMA; KERTADY; -.
DR   Proteomes; UP000078597; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd00577; PCNA; 1.
DR   Gene3D; 3.70.10.10; -; 1.
DR   InterPro; IPR046938; DNA_clamp_sf.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   NCBIfam; TIGR00590; pcna; 1.
DR   PANTHER; PTHR11352; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR   PANTHER; PTHR11352:SF0; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   SUPFAM; SSF55979; DNA clamp; 2.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|RuleBase:RU003671};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003671};
KW   Nucleus {ECO:0000256|RuleBase:RU000641}.
FT   DOMAIN          1..60
FT                   /note="Proliferating cell nuclear antigen PCNA N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00705"
FT   DOMAIN          116..242
FT                   /note="Proliferating cell nuclear antigen PCNA C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02747"
SQ   SEQUENCE   247 AA;  28449 MW;  A2DB2E679B94031D CRC64;
     MFECRIDGQF FKKLFETLKD ICTEVNLECD ENGIKMQSMD CSHVSLVDLN IMSDFFQHYR
     HILIKEKSTV FLFKEDSDND AVLNIGIIDE EEQSNTEDSL EIQVKLINTQ KEHLEIPQSE
     YHCQCTMKSK KFQEFTKYLN SIGDNVSISM KKDTMILSTT GSDIKVTKQF TNDMTDISIT
     CSKSVSQEFA TRYLVMFSRA SSLSDEVLIS LSPNIPVSIK FNFKQQLTEL QDNSHLTFFL
     APKIGEY
//