ID   A0A1A8Z248_9ACTN        Unreviewed;       248 AA.
AC   A0A1A8Z248;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Aquaporin Z {ECO:0000313|EMBL:SBT37955.1};
GN   ORFNames=GA0070621_0266 {ECO:0000313|EMBL:SBT37955.1};
OS   Micromonospora narathiwatensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=299146 {ECO:0000313|EMBL:SBT37955.1, ECO:0000313|Proteomes:UP000198765};
RN   [1] {ECO:0000313|EMBL:SBT37955.1, ECO:0000313|Proteomes:UP000198765}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45248 {ECO:0000313|EMBL:SBT37955.1,
RC   ECO:0000313|Proteomes:UP000198765};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC       {ECO:0000256|RuleBase:RU000477}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT594324; SBT37955.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A8Z248; -.
DR   PATRIC; fig|299146.4.peg.265; -.
DR   OrthoDB; 9807293at2; -.
DR   Proteomes; UP000198765; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015267; F:channel activity; IEA:InterPro.
DR   Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR034294; Aquaporin_transptr.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR022357; MIP_CS.
DR   PANTHER; PTHR45724:SF13; AQUAPORIN NIP1-1-RELATED; 1.
DR   PANTHER; PTHR45724; AQUAPORIN NIP2-1; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; Aquaporin-like; 1.
DR   PROSITE; PS00221; MIP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198765};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000477};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   248 AA;  25042 MW;  46CA4158EB5A9AD5 CRC64;
     MTARGEVIVD CTNPIWWRRL FGELLGTFLL VLVSVGPGVV NQRTGAEAVS RTAAVVAPGL
     MLSSIILFMG AVSGAHLNPS VTLAFALRRD FPWQRVPGYL VAQFAGAVAA GGLLAGTLGG
     HGTAGLTVPG PGIGAPLALL WELVLTVGLI STVLGTASCA QNVGPLAALA VGGYLALAGL
     WASPLTGASM NVARSLGPAL VYGQPRAWWA YLVGPLLAVP VAVGAAALLR GPGGGGISRR
     IAQGTVRR
//