ID   A0A1A8ZEG5_9ACTN        Unreviewed;       786 AA.
AC   A0A1A8ZEG5;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Adenylate cyclase, class 3 {ECO:0000313|EMBL:SBT42273.1};
GN   ORFNames=GA0070611_1924 {ECO:0000313|EMBL:SBT42273.1};
OS   Micromonospora auratinigra.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT42273.1, ECO:0000313|Proteomes:UP000199385};
RN   [1] {ECO:0000313|Proteomes:UP000199385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA   Varghese N.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT594323; SBT42273.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A8ZEG5; -.
DR   STRING; 261654.GA0070611_1924; -.
DR   PATRIC; fig|261654.4.peg.1958; -.
DR   Proteomes; UP000199385; Chromosome i.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199385}.
FT   DOMAIN          26..153
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          572..635
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          688..786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   786 AA;  81048 MW;  5A8AF6CD6EDC3FF4 CRC64;
     MPVSRTTRSR EPVTCWPVPE ERRTVSVLFV DIVGSTGLVE RLDPEDVRAL QHGYFGTVAG
     VLRRWSGVVE KYIGDAVMAL FGAHGSDGFD AYRAVRAGLE IQDALDRRAP DGTRLRIRVG
     IATGEVVVDL AAARDGGHGT ASGAVITTAA RLQGYAPPGG VVVCAATRRA TAGLLGLRPL
     GAVTVAGMAQ PLDVWRVTGL GRPGGSRHHG PLIGRRRELA SAADEIIRAL RERRPGRVSL
     VGPTGSGRSR LLHELTRVVS TVDGAPVRWC VAHCPPYPRG DLAPLADMVR AFAGARDTHP
     PAAVRRRLVV ALDGVLPPVP LGATAHDLAD FAATPLDTAV ATLGAQRWRE TLLALAARGP
     LVVAVDDLDR AAPPLHRFLH RLLATASARA LPLAVVVTHG PGRAEPVPDP AGRHRRVPLA
     PLRTVETGRL LRHLLGRAAR PAALARELLP LVAGNPAAAE AYVRALDGPA GPGRPVPDAV
     RRMVDARLDR LDGEQRAVLM AGAACPAEFD ADVVERLLGW PAGRAEPALR ALLVCGVLRR
     AGRRYAVGEP TVARVARQRL PRTLRAEFTR RARAEAEGCP AGAPARPDGT PPRPVADGGG
     ASTVAGRHPA CPPRADRPPA AGVAHRPGTV PRRLGPVPTA GVATRPVVAP APLTATAPQV
     AATPLLATAP LVAAPPGVRP GRASVAAAPA ARGVHRGRPA TAAAAGRHAA DQHRSPVTGT
     AGQGRSAVAD AAGRGRGPAI GAVPGGSVGA GRRAQPTRSR IDPPGTAPGS RLDGARGVGA
     PAPVAA
//