ID   A0A1A8ZFU2_9ACTN        Unreviewed;       353 AA.
AC   A0A1A8ZFU2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=O-methyltransferase {ECO:0000313|EMBL:SBT42747.1};
GN   ORFNames=GA0070611_2082 {ECO:0000313|EMBL:SBT42747.1};
OS   Micromonospora auratinigra.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT42747.1, ECO:0000313|Proteomes:UP000199385};
RN   [1] {ECO:0000313|Proteomes:UP000199385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA   Varghese N.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT594323; SBT42747.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A8ZFU2; -.
DR   STRING; 261654.GA0070611_2082; -.
DR   PATRIC; fig|261654.4.peg.2120; -.
DR   OrthoDB; 3804952at2; -.
DR   Proteomes; UP000199385; Chromosome i.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 1.10.287.1350; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SBT42747.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199385};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:SBT42747.1}.
FT   DOMAIN          115..330
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
SQ   SEQUENCE   353 AA;  37717 MW;  13C8EB7A9ED438C5 CRC64;
     MSKQTEQAPD LSIYTSLAEM IANFPKAQYA RALALLRIPD LTVAGPRPLA ELVGETGAHP
     ESLRRFLRAC VMLDLTVETA PEVFGMTRMG ALLHSASPFA AIARGTAGLQ HYVPYGYIVD
     TVLTGRPATK AALGMTFYEY LDANPDELRQ FGALTSITSG DCGEAVAAAV DLSAYPTIVD
     VGGNSGTLLG QLLTAAPGNR GVLFDRPAIV PAAREQLAGA GLADRVEVVG GDFFDRVPDG
     GDLYTLKNIL WDWDDADAAR ILATVAAAMP SGATLMIIDQ FLPEMPLGDG AELDPRTREL
     HRVSFSILLQ RGGRVRTEAE YRDLVTAAGL TVTEVLPAPG AKRRWDLLLA RRP
//