ID A0A1A8ZKA4_9APIC Unreviewed; 5364 AA.
AC A0A1A8ZKA4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Cysteine repeat modular protein 4 (CRMP4) {ECO:0000313|EMBL:SBT44321.1};
GN ORFNames=POVWA2_047690 {ECO:0000313|EMBL:SBT44321.1};
OS Plasmodium ovale wallikeri.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=864142 {ECO:0000313|EMBL:SBT44321.1, ECO:0000313|Proteomes:UP000078550};
RN [1] {ECO:0000313|Proteomes:UP000078550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Naeem Raeece;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FLRE01000172; SBT44321.1; -; Genomic_DNA.
DR Proteomes; UP000078550; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 4.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR15439; RETINOBLASTOMA-BINDING PROTEIN 6; 1.
DR Pfam; PF07699; Ephrin_rec_like; 2.
DR SMART; SM01411; Ephrin_rec_like; 7.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4191..4213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4220..4243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4297..4318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4556..4578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4616..4641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4666..4685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4691..4710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4730..4746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3283..3320
FT /note="Tyrosine-protein kinase ephrin type A/B receptor-
FT like"
FT /evidence="ECO:0000259|Pfam:PF07699"
FT DOMAIN 3648..3693
FT /note="Tyrosine-protein kinase ephrin type A/B receptor-
FT like"
FT /evidence="ECO:0000259|Pfam:PF07699"
FT REGION 1284..1343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2385..2406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2586..2648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3381..3428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4392..4421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4440..4493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5084..5183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 5253..5315
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1284..1340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2606..2624
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3381..3413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3414..3428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4392..4418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4457..4493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5089..5155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5364 AA; 628201 MW; 0BBA5DE5F4635341 CRC64;
MIYKKNIKNL GFSCFIIFIT FLVILLKRTK ASISASTFTY YNGIYDINVE LLETEYVSIF
NIKSDSPTEH GFEISNDYVI SDDNETKNCN VLNNSLGEII TKQTHTKKFL LVQKRDSKVY
IKDKKNLCST ISPVEKSSFP VQNVEQEGEY IKIGDIKNCS DENANKFIYY FNIIGDVVIS
EDEKCDKVVK SPLVKNAEVS NCSANIGIIS NINEFNNGIY YVCFKSKNQP VILTKFIIDK
PVPINSYYCN FENPNCTIIT SITLFNNIPN ITEDTLVLKS KCDDLNIPSI KNSHKLDGEY
YSFDFKNDRN TYYLEVCVIN NLKYKTVGYV FFLQVSNPIV CFVGSECVVK AFTSKEKIKY
IIRDIESTTF TWSATTCEGK NSGDKDINIH AKEEDKHIYI FSDNPLTSEN NLCSKYNGKY
LSLFKIDLID NPHHNVYYSV INGIVINYKA HIFEYNNYLG PYIKYECSDN EIVKDEYNSL
MDNDDNEFLY ESKKLYLHFN YYPVTLRLCL KQYNYYDIGS VRIERVINFK NVSLDPLMFV
GQVSIYKEDK NTRILKFAIK ENESCHSENG FFIQSKYSTD NKKMGEKIIG DTTLFYEGSN
KQNLDKFRYY ICMCSEEENC KDNNNLKDYY TYTNIYVGNN VAPVEKIKYV CKLFSNCSFN
VTFKSQHASD RWVSKTGTSC NTNDLVDIGI NFKKNEVLSD DTSEIIVVDF DIYYHSSNLN
KNLLNRDIII CGNYRDQSFV IIIETDLFLT YHTIPHGEFD IINIERSNLC FNKKILSIYS
YHDGKINLFK KLEIDEKTNA NKIKLKFEYD NLKNYETYFI RECHYCPGIL TYTHQEDDCI
FQNPNTEKEI YWGKIRYRNN IFNSLDKTMK IYNCSNVIMD NHTLTSVLLF DGPFREVEFH
CFIGVDCTHK EKFYFLWYKY SLFIEVTKTR RIIIYIQEKP KIRPTGSTMF HSIRISDVVL
KVPEQNTKGL IPGPYKIIYT RMWNGSISET YIGTFHFIGT PPKRYLITGN EKDIIINGYF
KNVEYDKMKI TKYTTCQFSE LLEENILKDY QENLQAEVLN NIQDCAYSDD YKLICKNVNT
KMDKFSLCWC YEVYENFCSI LKNMERSIIQ VSPVESAINP IIQITKSPHS NFMNFDILDY
FFLLEEDCSN IKNLFLKSQL NKEKDILDIY KTLEFPQKYD ICVCQVKEDV LCDKTGDFKR
LYIQMSQSEV RELMKIGINN FNAGIYPVKD FSFDIDFMEN LNNGMIPAMA FLPGPTEYKE
YICFAGVPCY ILIKVKILIN KKKDNPNNSN VEQGANSNSN SNSNSSSSSN NNNNNNNNNN
NNNNNNNNNN NNNNNDGNVR SNKNENKKNI KILHARTLLR DIGSIYYTLN DTKECKNEYG
KIYESEHGSS FSSQEINILN YRFIDGVYNL SIDVIPTDVT KMYEVCITFG INDQHYYNAG
NVVFYGIFRE HGSIGGGDGD REDNSSELVS GLPFNLEIKQ FYSKYDLFIR VAYQKYSIGK
TCHTDNRSKE KLFLDNSFEQ LVAHHEKEDV GNDVTSYKWK SLRVILDADN TNYTTYYKNK
DGTYNLFICS CYEITEGHCK SDEYYISEIT KFRVHTATLK EPKINSIIKF LKPFTLTLET
AKVLKGSIKI FPVDMMEDLD KLCLELIERR FYLQYAAETN GYEQKYNITI NFLSQGVVVC
WCPQEQCDNA DYLTKVGFFR TNSPHFLEVH TDINGYFSFT FLNDLININD RVRFVDRNST
CTSDSSVDLF EHTVEVNDIK YDTNWEQRIE IYGKPQKIEK EINENFMWIS KNYKITNDEE
KYIKICYCFY FYNKNCADTD SYTYIGFVLN NRLHKQISQN SLLIDETTNL RYLNRDSLKF
IALDSYNDYN RNICNSRNNQ SNAIVPFFEG RIFKYARNES TNLTIFKRKY TNEVNFVVCY
STFYYGNKSM FLLKGIDINE ISRQSNIIKY NYELNQSGFI FKSKLEESQV NNSEKEKKSN
EKSSLEERKS ERNIFHNYFF SKNFHMSPTM SDVYIRNDFQ QYSINGENIR ENVKIALSKF
YDTSSVDLNE LIYYKNRGDI FTNLQLEKIF FVDNKKVIFC CYDNDYVELE VDEHGKYFVN
KEPKINVLIG SLKQYHPDFT EDTQISYSTL LQLGNLRSKV SNYDYLMIEN SNEGGFYKNH
IFIHLKDSIF ELKIYGKDIP DHAYILHIIQ FNNRCYDLDR TLFHLENEVY VKNINFIVFN
GIQMDAINNY KLCIQDKSQN VFHDVGILNI TNYYIVHESF FNENYFPSNR EKRNVILNVC
IHNESHNAFV IKRNGSFYFT LDMKKIVFLK KSEKLYDPFP EIQHHQLISF DIDFDENYIY
VNDLQLKKIA RLQIVNAGVP MNIIGKRRSR RSTYDNELKT NQQREDDFKD KPGNRKILLG
NTKNKHSLHV RDTTRGSKYL GHLSQYPDHY AEQPEMFRKE KLLFSNKFSK RESVIANDAR
KRNDNRPNKL VQKIFLNLHT SEGGENKKYE NTISQQGARK KKTAKNTSEE EQTKVNKNVL
KKFYDIIINK KENLIYKNFR ELYGYLQKRV EGSSLIRSLH KLLDHGKMLK RKHIISNFLH
LFKEKMKQGH QRGRQNGSSN QMKDNHSEVR QNREPPDEEN SENGQKKGNL GGNYNFPEDS
RRKVRSRRSV AKNLEQSIYD SIIQENVKRF INTKEPPNYL PNNINYLEIK NLKNPLYITL
RDNLLYILDS TRNNFFSYNL TNKEVIELEA YNSSSHKFML SNPLNFSIYH GQLTEHTTNR
TNLAFVTQIK SNEIKIIDLS QKKYKIVKSI KLRKGYNHNN INKVIAIEQN LLIVTSQVND
DNIIYHYHFN SFDHYFRMSF NYTFSKNYNS NDILNVVPEI DKSSDFIIYF CFLNSKNKCT
NVDELTKLNI SHTTGAVTGK LNYFGNFNLK IFAKTHFQYK INTYKDLYSY CDVGKEFNKK
KNVCESCPVG TFWDSVKLIC EKCDKYVKNT STLKSGSKLL TDCLCSAGYE YSEKSQSCEQ
CKPGYYKGTS GNFICIKGCP INENSTVYGA TSYSEMLCKC IKGYYKKNDK CVLCLKNHYC
SGNNLIRACE ENKISPEGTK SKDDCICKEN FIYNYNQGIC SYCASVAKVS GDVIYCTLCQ
PQYLNRGIFA IPGEHNYGLV NVMYDYHEDL MLQGKTMQYA YFDGKSYERN SARFITFSRE
DAVGKIDHNK GGEGMPKFAI EVDMVNPSNC LFCDSGYFMD NKRRKCLPCS NKYCEGFSKT
PKGCPKNAIV NVKNASSIFD CLCKRGYGTM NERRNAINKK LICKACPKNF FKHNISDEFC
LPCPHGTYTL SEGSTSIRSC LPREGYFLLM FGNIDIEYLR YKFDVNSENR IYSYFENNDK
SFDNDVYDYF LRQNFEEFSG NAEKKQGKNP QMKEENDRKN DNVVERRNDN AIDQQRGNVD
NQQKSPSNMY NLQNLRNLGF LGRASLFYMY AVLLKNVEDN YRWESDSNLK VVCHVNVHSK
KNPMFTITYK PNLESCLHSC KTNVYCTGVE FSRKKVEYTE IFLKNNQKVF VGYFKCKHFY
FQNVYDYASP NLDTFLNEDV ENNIAERSPL AYTNFVLENK KNIIFTCTVD RDKKYLLYKY
YQLVGCFMGK FCPGNHTPYL ISCPSNSTTV VSLATNVDKC LCLKGYSYIG IVSHRCTICE
RGTYKNEIGN FKCENCPLTF STVNIGSTTI NDCSCTPGNY LTFDTLQNFI NLEKINYRNL
NDKYFIVPKK KKNNTYYMTE ITKISLNHLN REDDKEAIND TLKRPIAICR PCSLDNHYCE
GGIESNIIFN NAVIEGQVHT LPKKCPKDLV IPQGIKQRSS ISNCLCIHGK ILRTSKDKTV
ECFPCPPNTF KESEYDNNCS GACPHFSTTF VGSSYENQCF CKNNYFLVIT EDDHTKSKKS
KKSCKICPNG AICSRGFNVH LFLNLLKDRA YNNINVLDHE KPYPIYGYYA VYKQKNAHKL
WTPLDDNNDL KYSYPYYNLL LFIQKNIQKG NYFFFEKSQK LYLNEEFIKQ INEKNENKKK
SPTSDKKGEL HNLFISADVM SFLQSGEKYD TLKNEKDATP KYGSTALYAD GKKSVSSGEL
TQTLLSKQEE HFPLKSSNNI VHGEWDNDEK YSLEMFNKYV EEANELKVKN NKFERLPDIH
ACTIPDRCLG TITNLCYEGS TGYQCNSCEK NYDMSYFKSK CYRCRNLFHE LLYVIILKLV
YYVIVILIVS LNYNSCLNKL YISGILIKIW FNCSMNFIAF GFFSPANNSF ITKYWYLYKT
LFLYHLKLFS SYIRIGCLFH NYDIDVSYNK IWYTQKFIHI FTPLFDAISI TVILFVVIQI
CKLMYKREIQ NFEVILSKIP EIDEKYKLDF SAIEQTGEKT LEKGKMGKAG KIGKRSKMRK
IHLFKSKKRM EIEERLGKEE ERNEEESHKG EALTHDLEKN CDGGASAAAT AAATATATAA
TTAATTADGG GNNMKRGSME HAKRGETVMD ALKRKRAKEL RKDEKSKYDK DEIDETLNQH
GKGREDSNYE LKYVKKEDKM YRTFLNETVE YIYEKRIFGP WRFIHKKKEK FGKRMLMFLS
DTFPCYVLMI ALSIPYVLME MIQLVYCKPV KYKSQESELY LAYLTTQKCS LSSKSFLLGF
IVICFVILLC IFIWLVFLYL YSKRRKRKSF DKLLKNLLAG YRQGKAIFEL IFVLKNVILV
TIIAFNIHYH FYYIVLITLI LTMFAVLEIL SNPFDGRSFN ILNKSLRVGN VLNIFFALTI
WGSFYWNYET FFMFPIFFVL LYHLYMIHNI VREVILSRHF MHTQTVINIQ TQGYDENNIK
NKNYKIYYKV MNKIKFFLNK NQKEKILTFD KNTNQPINSN SITREHVKFE PIEDIIKRYN
LNLKAPGEIK PQNKDIVEEN KKEKENFSIK KNILPRNIHN VAHIWYDEQN EDLFFLMPYE
NKFYLSFAND KPKKDEKKSM FYLISNYVTD KRRKKNIKYF VSAIIEIIDK FLGASRSCSI
YENWFDFSMR FAFVYISWIK KMNERNTVIP STMDQLKLNL DQFIYIPLFY KFEQFIQQKR
AINISPNGTL RNYTNEHSVE MLEKKNSFQN TEIKISRSYG SYNQMKSLKN RKHIGEKIDK
NENLREDASS GNDVHSDNSL DKEEKETKKK NSEENEEMDV LRYLRKKEMK KKGEKTKPEK
KRFKKRKGNS THNNEKGDIP TVKNHDENIL NYSMDIFSSE MFNEDSFNML ISLFELYIAM
KALKTMDPHI FSKLYNLYNE KYIKFEKSLM FYINKLRDEI KLEIEEIDNE ISKGDTTEKM
RVKKYYYYKE ELNKRKKLEE ELLTKIKKLE ECIEANKRSQ SLRNMLTNPR ILNEYSGNIG
DDINYIFSLL QNEGTYKLNH SNKE
//
