ID A0A1A8ZM61_9ACTN Unreviewed; 564 AA.
AC A0A1A8ZM61;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase {ECO:0000313|EMBL:SBT44948.1};
GN ORFNames=GA0070611_2858 {ECO:0000313|EMBL:SBT44948.1};
OS Micromonospora auratinigra.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT44948.1, ECO:0000313|Proteomes:UP000199385};
RN [1] {ECO:0000313|Proteomes:UP000199385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT594323; SBT44948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A8ZM61; -.
DR STRING; 261654.GA0070611_2858; -.
DR PATRIC; fig|261654.4.peg.2907; -.
DR OrthoDB; 144293at2; -.
DR Proteomes; UP000199385; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF55; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE DEGS; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SBT44948.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199385};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 363..549
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 537..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 59402 MW; B2905909CBE96EC5 CRC64;
MSASTASQPQ TRPIAAAARV VLLALVAALT LFATGELAPL WWIALLGIAG LPAVLAPQHR
QLGLLSRFAE VVVLGLAASQ IAAATHLTGV TGGLGASAVL PYLAVPVTVT ALRRRYAEGV
ALLVVAAATL LLSAAFTEVD GGRQLGQLGY LAVCAQWLIL AGLGIWTAVT FQRVVRVRGE
GKPQPYAEAT RLLTQLRTVA RQLPGATLDP GGISEHLLEE LRMVARTDRG AVLSASGGGR
LVVLAQIGAD RVDWETTLDA DSAIADAWAS QQPQTSSRSQ ARSRQSGQVS ALIVPLVAGV
RTVGLVVIEA DAAHAYPAAV MSRVTALTGP AALRLEAALL FDEVRSLATN EERQRLAREI
HDGVAQELVM VGYGIDNALA YVDEDPKETA EALRTLRQEV TRVITELRLS LFELRSEVDR
HGGLAAAIAE YARTVGASGG LRVHLSLDES TARLPAATEA ELLRIAQEAV TNARKHAGAS
NLWVTCEVDP PYAQIEVSDD GHGIGDQRPD GHYGLAIMAE RAERIRGRLE ISPRQPSGTT
VAVVLGSSPR RDKVRGSAAA AEGE
//
