ID A0A1A9A056_9ACTN Unreviewed; 484 AA.
AC A0A1A9A056;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=GA0070611_4452 {ECO:0000313|EMBL:SBT49526.1};
OS Micromonospora auratinigra.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT49526.1, ECO:0000313|Proteomes:UP000199385};
RN [1] {ECO:0000313|Proteomes:UP000199385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LT594323; SBT49526.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9A056; -.
DR STRING; 261654.GA0070611_4452; -.
DR PATRIC; fig|261654.4.peg.4510; -.
DR OrthoDB; 9757990at2; -.
DR Proteomes; UP000199385; Chromosome i.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SBT49526.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199385};
KW Transferase {ECO:0000313|EMBL:SBT49526.1}.
FT DOMAIN 270..484
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 484 AA; 51925 MW; 5B057A90DF79C266 CRC64;
MSERTDFTAL IAGHTGVIAM INAGESGLSV LTRLLRVVEP AVGAAGLVWV EFAPAGGRVI
AATGSAEFVV GRPLPATDPA TVCLLSGPPV REVRVDAIPG ALPVEVAGRG LCRMIVARAE
IGGLTVGSLH ALYPEGEPLD ESQRAVIGYV AACIGHMYGD QTGLPVHGDG PVVAALADGL
AVVDREHHVR LWNPAAAQVT GRPAEQALNR PLPFPLPPSG QVLDHRLPDG RWLRITAGEL
PGPGALRVVT FRDITDQQRR DHDRDLFVAV TSHELRTPVT VIKGYADTLT DHWESLSDDD
RRQAARIIGQ RANELARLVD RLLTTATEHR PGGEPAAPFD LVDALRGAVS DLPADVRHRI
VLDLPDDLPK ALGDRHSLAT VLTELGTNAG KYSLPDTPIE VTAEANERTV SFRVADRGIG
IRPEHVERAF DRFWQGESGD RRRYPGAGLG LYLVRQIVEQ QNGWVSLRPR TGGGTVAEVR
LPRG
//
