ID A0A1A9A5V3_9ACTN Unreviewed; 484 AA.
AC A0A1A9A5V3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Leucyl aminopeptidase {ECO:0000313|EMBL:SBT51480.1};
GN ORFNames=GA0070611_5199 {ECO:0000313|EMBL:SBT51480.1};
OS Micromonospora auratinigra.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT51480.1, ECO:0000313|Proteomes:UP000199385};
RN [1] {ECO:0000313|Proteomes:UP000199385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
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DR EMBL; LT594323; SBT51480.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9A5V3; -.
DR STRING; 261654.GA0070611_5199; -.
DR PATRIC; fig|261654.4.peg.5267; -.
DR OrthoDB; 9809354at2; -.
DR Proteomes; UP000199385; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR000819; Peptidase_M17_C.
DR InterPro; IPR008283; Peptidase_M17_N.
DR PANTHER; PTHR11963:SF53; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR Pfam; PF02789; Peptidase_M17_N; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000313|EMBL:SBT51480.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000199385}.
FT DOMAIN 331..338
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 484 AA; 50331 MW; 524AF3078BF4208D CRC64;
MLAIRLVGGP ERPDTLVLPV RPPGPDASAE LVPTDVAPAD GLRAEATALL PVARLTGEAG
EVREQLRPGG TPARLVLLGV GAGDEPAWRS AGAALARAAK DETQITIALP ADPAAVRGLA
EGLLLGSYRY RLTEAGPAPA LAEVDLLVSD PDALAPALDT ARTTAGMTRL ARDLTNTPSS
TKNPAWFVAQ VEEAAAGRPD LHVRVRGPEE LAAEGFGGLL AVGGGSASGP RLLELDWRPA
DARTHVVLVG KGITFDTGGI SIKPVAAMTL MRKDMAGAAA VVAATLGAAA LRLPVRITTL
APLAENMVSG SAFRPGDIIR HYGGLTSEST NSDAEGRLVL ADAMAYAARE LKPDLLVDLA
TLTGANAVAL GKRHGALYSD NDRLAADLLA AIEAAGERAW RMPLPADYVE YLGSELADLH
SSPEPAKSIT AALFLREFTG ELRDRWVHID MSAPSWSEDA HAELTKGATG WGVRGLLRWL
ATLG
//
