ID A0A1A9A9A4_9ACTN Unreviewed; 642 AA.
AC A0A1A9A9A4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family {ECO:0000313|EMBL:SBT53061.1};
GN ORFNames=GA0070611_5933 {ECO:0000313|EMBL:SBT53061.1};
OS Micromonospora auratinigra.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=261654 {ECO:0000313|EMBL:SBT53061.1, ECO:0000313|Proteomes:UP000199385};
RN [1] {ECO:0000313|Proteomes:UP000199385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44815 {ECO:0000313|Proteomes:UP000199385};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT594323; SBT53061.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9A9A4; -.
DR STRING; 261654.GA0070611_5933; -.
DR PATRIC; fig|261654.4.peg.6005; -.
DR OrthoDB; 155529at2; -.
DR Proteomes; UP000199385; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR PANTHER; PTHR14859; CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR; 1.
DR PANTHER; PTHR14859:SF18; ENDO_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:SBT53061.1};
KW Exonuclease {ECO:0000313|EMBL:SBT53061.1};
KW Hydrolase {ECO:0000313|EMBL:SBT53061.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Nuclease {ECO:0000313|EMBL:SBT53061.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199385};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 418..632
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF03372"
SQ SEQUENCE 642 AA; 65324 MW; 3CB2DFC3AA711D3B CRC64;
MRHRHLPTAA VALGVAVLLD VLRVWLPSII TIFGRAAETP AELLGAFALC WFLLALAAPS
LVRRLGSRPV GLVAAGTLAA SRLALTAAPG GRAQLWLACA GLLAGLVWLA ATAASVDRPV
PGLALGLAGA AVGHGLLGTE DLVWRGGVLG WTLSVLLVLA FLAASAATPA PPAAAPTTGT
GTAARVTGAR SWLLLGPALL LAGQVALAPA LWSAAFVSGS RDFPGLYRSS VGSSSLLPVF
PVLFFLLAAL HWPATRLVRV LWPVVLLVGA GLFAAGWLVP AMLLTGVGLG GCLALTDTAA
TKAAGPDGAA RGVPGADGVR RGYAAVGGML VFAVATVVYY ATYDLGYPNG WVPVGTAVLV
ALVAFAGPST ATPVLTGTPR WASVAPLVLL TVVALEIHRP VPTAVPPRTP ATVVRVVAYN
IRMGFGLDGR LDLDAVARVV RAGRADVVLL SEVDRGWLLN GGHDTLALLA QRLRLPYVFA
PAADPVWGDA VLSRFPVRSG RTRPLAAHGA PTGAQALGIT LDLGGRELAV VATHLQPPPG
RGPVAQAREV AAFATRYAAG RPLVLGGDLN TEPGEPAFTA FTAAGLVDAL AAARPLPTSP
ADDPRQQIDH VFVSPGIGAA DVAAPRSTAS DHLPVAVTLT LP
//
