ID   A0A1A9A9F2_9ACTN        Unreviewed;       352 AA.
AC   A0A1A9A9F2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=tryptophan--tRNA ligase {ECO:0000256|ARBA:ARBA00013161};
DE            EC=6.1.1.2 {ECO:0000256|ARBA:ARBA00013161};
GN   ORFNames=GA0070621_4563 {ECO:0000313|EMBL:SBT52829.1};
OS   Micromonospora narathiwatensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=299146 {ECO:0000313|EMBL:SBT52829.1, ECO:0000313|Proteomes:UP000198765};
RN   [1] {ECO:0000313|EMBL:SBT52829.1, ECO:0000313|Proteomes:UP000198765}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45248 {ECO:0000313|EMBL:SBT52829.1,
RC   ECO:0000313|Proteomes:UP000198765};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363036}.
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DR   EMBL; LT594324; SBT52829.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A9A9F2; -.
DR   PATRIC; fig|299146.4.peg.4714; -.
DR   OrthoDB; 9801042at2; -.
DR   Proteomes; UP000198765; Chromosome i.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00806; TrpRS_core; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002305; aa-tRNA-synth_Ic.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR002306; Trp-tRNA-ligase.
DR   NCBIfam; TIGR00233; trpS; 1.
DR   PANTHER; PTHR43766; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43766:SF1; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00579; tRNA-synt_1b; 1.
DR   PRINTS; PR01039; TRNASYNTHTRP.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363036};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363036};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363036};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198765}.
SQ   SEQUENCE   352 AA;  39636 MW;  3BCC290D4FFA0827 CRC64;
     MSAARMLTGD RPTGRLHLGH YVGSIANRVR LHRRYESFFI IADLHMLTTR NTREDIERVS
     RNAREMVTDV LAAGVEPDRA TFYLQSAIPE VGDLNTLFQN LVTVPRLERV PSLKEMSRDA
     GKEEMPYGLL GYPVLQAADI LCVKGQVVPV GKDNAAHVEV TREIARRFNH LYGEVFPVPE
     MIMSETPTLV GTDGQGKMSK SRGNAIALSD DPATVRRKVM GMYTDPNRVR ADVPGTVEGN
     PVFAYHDVFN PDRAKVEELK ARYRVGRVGD VEVKEELAVA LNRFLDPVRE RRARFEAASG
     LVDELIFEGT ERTRTEVRRT LVEVRRAMGL TSAYTQVRRR AERYRKTVAT PA
//