ID A0A1A9AC30_9ACTN Unreviewed; 315 AA.
AC A0A1A9AC30;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=B12 binding domain-containing protein {ECO:0000313|EMBL:SBT53753.1};
GN ORFNames=GA0070621_4953 {ECO:0000313|EMBL:SBT53753.1};
OS Micromonospora narathiwatensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299146 {ECO:0000313|EMBL:SBT53753.1, ECO:0000313|Proteomes:UP000198765};
RN [1] {ECO:0000313|EMBL:SBT53753.1, ECO:0000313|Proteomes:UP000198765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45248 {ECO:0000313|EMBL:SBT53753.1,
RC ECO:0000313|Proteomes:UP000198765};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT594324; SBT53753.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9AC30; -.
DR PATRIC; fig|299146.4.peg.5110; -.
DR OrthoDB; 9800334at2; -.
DR Proteomes; UP000198765; Chromosome i.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000198765}.
FT DOMAIN 5..74
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 190..312
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 315 AA; 32649 MW; A55B2232D77A7EDA CRC64;
MADEALSAGA VARTLGVAVT TLRTWHQRYG LGPSEHVPGH HRRYTSTDLS RLEIMRRLTA
DGVSPAEAAR WARRAPVLAA PERLGRATPP GVTRAGGGTA IPVGRAGPVA RGLARAAMRL
DSVAIGETIA HALAADGVVT TWDILLRPVL AGIGDRHAAT GRLIEVEHLL SRCVSEAFAT
VARARPAAGP ARILLSCADE EQHTLPLEAL GAALAEAGVG YRMLGARVPV PALVEAVART
GPTAVVLWSH TGATADPDQL TALLATPRRP LLVLAAGPGW RADALPAGVV RPMDLAEAVA
LATAVRDSQD RSTTA
//
