ID   A0A1A9B9W2_9ACTN        Unreviewed;       606 AA.
AC   A0A1A9B9W2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:SBT65687.1};
GN   ORFNames=GA0070622_2690 {ECO:0000313|EMBL:SBT65687.1};
OS   Micromonospora sediminicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=946078 {ECO:0000313|EMBL:SBT65687.1, ECO:0000313|Proteomes:UP000199558};
RN   [1] {ECO:0000313|EMBL:SBT65687.1, ECO:0000313|Proteomes:UP000199558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45794 {ECO:0000313|EMBL:SBT65687.1,
RC   ECO:0000313|Proteomes:UP000199558};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FLRH01000003; SBT65687.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A9B9W2; -.
DR   STRING; 946078.GA0070622_2690; -.
DR   OrthoDB; 4477213at2; -.
DR   Proteomes; UP000199558; Unassembled WGS sequence.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          532..606
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   REGION          515..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..533
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   606 AA;  64673 MW;  722847D576056307 CRC64;
     MALLASASTP TPAPDRTDAD WRSVVSRFEQ VVAAHPDRPA LVFGSTVLTF GELARRSAAV
     DDGLRSRGVG TESLVGLLLP RGVDLVVALL GVLRSGAGYL PLDPTLPAAR LRYICDRGDV
     TLVLSDAGSR RRLPAASARR ILTVDTCARA VTGGAPDRAE IRPAHRAYVI YTSGSTGHPK
     GVEVTHGSLA SLVDALAPVV GPAPARVGWN ASPSFDASVQ QWSRLCRGDT VVLVGDEVRA
     DPEAMATLIA EQRLDELDIT PSHLVSLLEH LPVENRDRPL RLLVGGEAVP AGLWGRLAEL
     NAAGVLAPIN LYGPTECTVD ATYARIDGSG GPHLGAPLAG VQVHLLDDRL EPVPPGGDGE
     LYVAGTGVSR GYLGQPGLTA QRFVPDIVAG DGRRMYRTGD RARIGPEGRL EYLGRRDDQV
     KLRGYRIELG EIEAVLGRCP GVAQAVAVAS TDLPGGEGLV GYCRLDRDAE GRPVPFDAEA
     VRRVVGQHLP DYMMPSVLVE IDRFPLTRNG KIDRAALPPP VRPEREEGQE TTPRSPTERL
     LAEAWCAVLG VDRVGVDDNF FDIGGQSLLA IRLVALLRRR TGRSVPLVTV FKHPVLRQLA
     AYLDDA
//