ID A0A1A9C2D0_9ACTN Unreviewed; 1091 AA.
AC A0A1A9C2D0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glycosyl hydrolases family 2, TIM barrel domain {ECO:0000313|EMBL:SBT93874.1};
GN ORFNames=GA0115233_107328 {ECO:0000313|EMBL:SBT93874.1};
OS Streptomyces sp. DI166.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839783 {ECO:0000313|EMBL:SBT93874.1, ECO:0000313|Proteomes:UP000198690};
RN [1] {ECO:0000313|Proteomes:UP000198690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DI166 {ECO:0000313|Proteomes:UP000198690};
RA Varghese N., Submissions Spin;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; FLSP01000073; SBT93874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9C2D0; -.
DR STRING; 1839783.GA0115233_107328; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000198690; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.90.182.10; Toxin - Anthrax Protective Antigen;domain 1; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF07691; PA14; 1.
DR SMART; SM00560; LamGL; 1.
DR SMART; SM00758; PA14; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SBT93874.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198690};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..1091
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008384944"
FT DOMAIN 51..195
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
FT REGION 306..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1091 AA; 119440 MW; 4A7532E8D25378F6 CRC64;
MTEHRTRPRA RMWALLAAAA LILPPMGLMP SAVAAEQSAD ASATAASQDA VQTHGLKGEY
FRMSAPGARD FAELGGTLLD PQINFSGLTS TFEELTGRTE HTTARWTGKL TAPTTGDYTF
HAIGDNGFRL FIDGEPVIDH WVGDWDREQT SSPVRLTAGE PHEFRLEMFQ DTGGANMFLR
WSTPTLPKQL VPMSAFTPPD DFEIYPVEPS VKEDGKRVRL RFDGRVGGLG TVKEHLKIEA
DTTAMPIRSV TSYPGDRNSA LVTLSEPVQK NQQVRVSYDG QGGLSAGGES VPKLIRYAEN
DSAHRLTTPW GDKVDTKNPL PEYPRPQQVR SQWKNLNGPW QFSGAEEGEE PVFGKNLDEK
IIVPFPVESQ LSGLERHEDH MFYRKLVDVP SSWKVGKGDR NNRLKLNFGA VDYKARVYVN
GTKVADHTGG YNAFSVDVTD ALKGTGKQEI VVAVTDTGGA NQPMGKQTTN PGGIFYTQTS
GIWQTVWMEP VAAASIDDIV ATPDIDTSSL AMKVRSDAAS STARVEAVAR DARGKVVGRV
SGPANKDLRL PVAKQHLWTP DDPYLYDLDV RLTDGRSTDR VSSYFGMREV GIKKVGGFNK
LVLNGKPIFS LATLDQGFWP DGLYTAPSDE ALAFDLKAHK KLGFNAVRKH IKVEPDRWFY
HADKLGLLIW QDFVSGNITN ETGQKAFVDQ GREMMRQHHN SPSVIGWIVF NEGWGEWNRE
ETGRITDAVK EADPSRVVNA HSGVNCCNSK GDSGRGDIID HHDYNNTDPA FPDERRAAMD
GEHGGFTLRT PGHMWPGAPT VIYSGVTTKA ELTRKYVENT EQFYLDQAGA ELSGSVYTQI
TDLENELNGL YTYDRREIKV DPAPVRDINR RIIAAGAAAG SQKPLTGGGH WKLDENSGTT
ADDEGPNDRP LTLREGASWT PGVSGSALKF DGQKQYAETA GPVLDTAGSY SVAAWVRLDQ
VPGNYATAVS QDSRATANSF YLQYGHGNFA FSTPDERRAT APVSVERGRW YHLVGVRDAT
TNQIRLYVDG ELAATATGGA ALPSTGPLTV GRAHWDGSKV DFWNGAVDEV HAFDKALTAK
EVGDLYGDEK P
//
