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Database: UniProt
Entry: A0A1A9EXZ4_9GAMM
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ID   A0A1A9EXZ4_9GAMM        Unreviewed;       355 AA.
AC   A0A1A9EXZ4;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=A8C75_09485 {ECO:0000313|EMBL:ANG62692.1};
OS   Marinobacterium aestuarii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Marinobacterium.
OX   NCBI_TaxID=1821621 {ECO:0000313|EMBL:ANG62692.1, ECO:0000313|Proteomes:UP000078070};
RN   [1] {ECO:0000313|Proteomes:UP000078070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST58-10 {ECO:0000313|Proteomes:UP000078070};
RA   Baek K., Yang S.-J.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ANG62692.1, ECO:0000313|Proteomes:UP000078070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST58-10 {ECO:0000313|EMBL:ANG62692.1,
RC   ECO:0000313|Proteomes:UP000078070};
RX   PubMed=29303694; DOI=10.1099/ijsem.0.002561;
RA   Bae S.S., Jung J., Chung D., Baek K.;
RT   "Marinobacterium aestuarii sp. nov., a benzene-degrading marine
RT   bacterium isolated from estuary sediment.";
RL   Int. J. Syst. Evol. Microbiol. 68:651-656(2018).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CP015839; ANG62692.1; -; Genomic_DNA.
DR   RefSeq; WP_067381226.1; NZ_CP015839.1.
DR   EnsemblBacteria; ANG62692; ANG62692; A8C75_09485.
DR   KEGG; mars:A8C75_09485; -.
DR   KO; K01626; -.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; GCF_001651805:G1ETP-1919-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000078070; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000078070};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078070};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       45    339       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   355 AA;  38822 MW;  5997D5B9AFA1FB80 CRC64;
     MTDIRVEDLN IDSHSVLITP DALKQKLPIS DAAAETVMEG RKVIRDILDK KDHRLFVVIG
     PCSIHDPVAA IEYGQRLKAL AEQVKDSLYL VMRVYFEKPR TTVGWKGLIN DPHMDDSFDI
     EEGLHIARKL LLDLSEMGLP LATEALDPIS PQYMQDLIAW SAIGARTTES QTHREMSSGL
     SCAVGFKNGT DGGLAVAINA LQSVSHPHNF LGINPSGEVS IIRTKGNQYG HVVLRGGNGK
     PNYDSVNVTL CEQALEKNSL ARNIMVDCSH ANSNKDPALQ PLVAENVANQ ILEGNKSLVG
     LMIESNLGWG SQSIPANLSE LKYGVSVTDA CIDWDTTEKS ILKMHAQLKD VLPKR
//
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