ID A0A1A9GKI5_9ACTN Unreviewed; 835 AA.
AC A0A1A9GKI5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Alpha,alpha-trehalose phosphorylase {ECO:0000313|EMBL:ANH38857.1};
DE EC=2.4.1.64 {ECO:0000313|EMBL:ANH38857.1};
GN Name=treP {ECO:0000313|EMBL:ANH38857.1};
GN ORFNames=I601_2439 {ECO:0000313|EMBL:ANH38857.1};
OS Nocardioides dokdonensis FR1436.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1300347 {ECO:0000313|EMBL:ANH38857.1, ECO:0000313|Proteomes:UP000077868};
RN [1] {ECO:0000313|EMBL:ANH38857.1, ECO:0000313|Proteomes:UP000077868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FR1436 {ECO:0000313|EMBL:ANH38857.1,
RC ECO:0000313|Proteomes:UP000077868};
RA Kwon S.-K., Kim K., Kim J.F.;
RT "Complete genome sequence of a soil Actinobacterium, Nocardioides
RT dokdonensis FR1436.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
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DR EMBL; CP015079; ANH38857.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9GKI5; -.
DR STRING; 1300347.I601_2439; -.
DR KEGG; ndk:I601_2439; -.
DR PATRIC; fig|1300347.3.peg.2432; -.
DR Proteomes; UP000077868; Chromosome.
DR GO; GO:0047656; F:alpha,alpha-trehalose phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF13; GLYCOSYL TRANSFERASE-RELATED; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Glycosyltransferase {ECO:0000313|EMBL:ANH38857.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Reference proteome {ECO:0000313|Proteomes:UP000077868};
KW Transferase {ECO:0000313|EMBL:ANH38857.1}.
FT DOMAIN 27..293
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 355..717
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 727..789
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT REGION 804..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 518
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 389..390
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 630..631
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 835 AA; 93238 MW; 34EDCCFE34338C74 CRC64;
MNRDRLGGGQ DPMDRGRFPV HPWRLVERGH RAADLGVTET LFAVANGYLG MRANPEEGRD
AHAHGTFVNG FHETWPIRHA ESAFGFAQTG QTIVNVPDAK LMKLYVDDEP LILGTADLER
YERSLDFRDG VLRRSLVWRT PSGKRVKVES TRMVSMTQRH LALLSLTVTM LEGDAPITIS
SQLLNRQDGT DEYHDPRAAM GEGIDPRKAS AFEDRVLVPR LHSAQDERMM LGYSCANSRM
TIAVAADHQL TTTDPSEVVR RAEADLTKMV FRVEATEGQP VRLQKTVAYH TSRGVPVREL
ADRCERTLDR SRRHGLDHYL DEQRDWYADF WSGADVEVTS PDADDEQIAV QQAIRFNLFS
LAQATARADQ QGVPAKGVTG SGYEGHYFWD SEIYVAPFLT YTQPHLARNL LHFRSRMLPA
ARHRAREMAQ NGALFPWRTI NGEEASAYYA AGTAQVHIDA DVAHALTKYV AASGDVGFLV
RDGIDILVET SRMWADLGFW RSNGTPSFHI HGVTGPDEYT TVVNNNLFTN VMARDNLEQA
VAAVDMVRRE HPEDFTQICA RLDLRDDEVE EWARCAAGMH IPFDEGLGIH PQADAFLDRE
VWDLSQTPDR LRPLLLHYHP LVIYRFQVLK QADVVLALFL QGDRFTAEEK RADFEYYDPI
TTGDSTLSAV VQSVVAAEVG YADAAWSYFC NALYVDLANL HGNTDDGLHI ASAGGVWAAL
VNGFAGMRDH GGRLSFDPRL PDAFPVLRCS LRWQQHRLRL ELTATRLLVT MVEGTGPVHL
SVRGTEHTVS AERPLEIDLD ARGTRLPHPL DERPQLGGTR ADGSRITAGV PAPTI
//
