ID A0A1A9I8W9_9BACT Unreviewed; 753 AA.
AC A0A1A9I8W9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=A8C56_21505 {ECO:0000313|EMBL:ANH84128.1};
OS Niabella ginsenosidivorans.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niabella.
OX NCBI_TaxID=1176587 {ECO:0000313|EMBL:ANH84128.1, ECO:0000313|Proteomes:UP000077667};
RN [1] {ECO:0000313|EMBL:ANH84128.1, ECO:0000313|Proteomes:UP000077667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS26 {ECO:0000313|EMBL:ANH84128.1,
RC ECO:0000313|Proteomes:UP000077667};
RA Im W.T., Siddiqi M.Z.;
RT "Niabella ginsenosidivorans BS26 whole genome sequencing.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; CP015772; ANH84128.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9I8W9; -.
DR STRING; 1176587.A8C56_21505; -.
DR KEGG; nia:A8C56_21505; -.
DR Proteomes; UP000077667; Chromosome.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048671; RecQ-1-like_HTH.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF21220; RecQ-1-like_HTH; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ANH84128.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077667}.
FT DOMAIN 48..220
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 247..396
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 555..635
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 85454 MW; E76B9358A84BB112 CRC64;
MKSEKKATKT KQPAVKSTKK TKGGIDLHGE LLKNFGFQKF KGKQEAIIES LLSGKDTFVI
MPTGGGKSLC YQLPAVIMEG VAIIVSPLIA LMKNQVDLVR GYNSNDEVAH FLNSTLTKKE
IKEVHDDLLS GKTKLLYVAP ETLTKQENLT FFSDLNISFF AVDEAHCISE WGHDFRPEYR
RLREMMNQIN PNAAVIALTA TATPKVQSDI IKNLGLKDAN IFISSFNRDN LYYEIVPKIS
KKQTNESIVR FIKSMKNKSG IIYTLNRKTT EELADILMAN GIKAVAYHAG LDSKLRAERQ
DQFLNEDVQV IVATIAFGMG IDKPDIRFVI HYNISKSIEN YYQETGRAGR DGLEGKCLLY
YSHKDVSKLE HLMRDKPLSE REVGAQLINE TVAYAESGVC RRKVILSYFG EQYDVENCGQ
CDNCKHPKER LEAKEQAVLV LKTIKELDER FATDYTVNIL IGKLTPQVKM FRHEGLSSFG
AGKDHDSLFW NSLIRQMLLE NLLKKDIEEY GVLKLTPEGT AFLKKPKAFT IVLNNKFEEA
WDDDEAPAAE DGGGAATDQQ LFEMLKELRQ KEARRKSLPP FVIFLENSLM DMATLYPTTI
AELEKCQGVS KGKAIRYGKP FVDLIARYVE DNNIQKPDDF VMKSVVNKSG NKVYIIQQTD
KKIPLETIAK NKGWKIDELL EEMETIAASG TKLNLGYAID EMLDEEDQDE IIEYFKSCET
SSLQLAQEEL AEYDFNWEQL KIMRIRFLSE YGM
//
