ID   A0A1A9LER7_9FLAO        Unreviewed;       923 AA.
AC   A0A1A9LER7;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280};
DE            EC=1.2.4.2 {ECO:0000256|ARBA:ARBA00012280};
GN   ORFNames=A7A78_10920 {ECO:0000313|EMBL:OAD91760.1};
OS   Aequorivita soesokkakensis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Aequorivita.
OX   NCBI_TaxID=1385699 {ECO:0000313|EMBL:OAD91760.1, ECO:0000313|Proteomes:UP000077552};
RN   [1] {ECO:0000313|EMBL:OAD91760.1, ECO:0000313|Proteomes:UP000077552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSSK-12 {ECO:0000313|EMBL:OAD91760.1,
RC   ECO:0000313|Proteomes:UP000077552};
RA   Thevarajoo S., Selvaratnam C., Goh K.M., Chan K.-G., Chong C.S.;
RT   "Genome sequencing of Vitellibacter soesokkakensis RSSK-12.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAD91760.1}.
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DR   EMBL; LXIE01000010; OAD91760.1; -; Genomic_DNA.
DR   RefSeq; WP_068761393.1; NZ_LXIE01000010.1.
DR   AlphaFoldDB; A0A1A9LER7; -.
DR   STRING; 1385699.A7A78_10920; -.
DR   OrthoDB; 9759785at2; -.
DR   Proteomes; UP000077552; Unassembled WGS sequence.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   CDD; cd02016; TPP_E1_OGDC_like; 1.
DR   Gene3D; 3.40.50.12470; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.50.11610; Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain; 1.
DR   Gene3D; 1.10.287.1150; TPP helical domain; 1.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR042179; KGD_C_sf.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   NCBIfam; TIGR00239; 2oxo_dh_E1; 1.
DR   PANTHER; PTHR23152:SF4; 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1; 1.
DR   PANTHER; PTHR23152; 2-OXOGLUTARATE DEHYDROGENASE; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT   DOMAIN          584..777
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   923 AA;  105442 MW;  3A77DEBE73CE4D28 CRC64;
     MDKFSFLNAV HPSYIAELYE KYLQYPDSVE PSWRAFFQGF DFGSENSAHE FFGTNEAVEA
     PQYAEGANCE DVVKEFQVVK LIDGYRTRGH LFTKTNPVRE RRKYTPTLAL ENFGLSQHDL
     KATFKAGEIL GIGEATLEEI IRHLESIYCD SIGIEYMYIR KPNEIQWIQE KLNINDNQPN
     FSTEHKKHIL KKLNEAVAFE SFLHTKYVGQ KRFSLEGGES LIPALDALIE NAAEKGVEEF
     VMGMAHRGRL STLTNIFGKS AKDIFSEFDG KDYAQDIFDG DVKYHLGWTS KRKTESGKEI
     NLNIAPNPSH LETVGAVVEG ITRAKQDDHH KNNPNKVLPI IVHGDAAIAG QGIVYEIVQM
     AQLDGYKTQG TIHIVVNNQI GFTTNYLDAR SSIYCTDVGK VTLSPILHVN ADDVEAVVHA
     MLFALDFRME FGRDVFIDLL GYRKYGHNEG DEPRFTQPKL YKAIAKHENP RDIYAEKLIA
     QGVIEKGFTD KLEQEYKDKL EESLENSRKE DKTTITPFMQ DEWEGYEYAE EDKMMETVNT
     KFDLKKLDEI AEVITKLPED KKFLKKIAKL VEARHTMYFE DNKLDWAMGE LLAYGTLLKE
     GHDVRMSGQD VERGTFSHRH AVIKVEDSEE EVVLLNHLKG DQGDFYIYNS LLSEYGVVGF
     DYGYSMASPK TLTLWEAQFG DFSNGAQIMI DQYISAAEDK WKLQNGLIML LPHGYEGQGA
     EHSSARMERY LQLCANDNMF VADVTTPANL FHLFRRQLKV NYRKPLIVFT PKSLLRHPKV
     VSTKEELANG SFQMLIDDAE AKATKVKTLV FVTGKFYYDL LEKREELKRD DVALVRVEQL
     FPLPTDAMKK IIKKYKNADD VVWAQEEPKN MGAYSHVLMH FEEARNFRVC SRKMYAAPAA
     GSSVRSKARH AKVIENVFDK NMD
//