ID   A0A1A9NBT1_9BURK        Unreviewed;       449 AA.
AC   A0A1A9NBT1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Dihydropyrimidine dehydrogenase {ECO:0000313|EMBL:OAJ63643.1};
GN   ORFNames=A6V37_20135 {ECO:0000313|EMBL:OAJ63643.1};
OS   Paraburkholderia ginsengiterrae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=1462993 {ECO:0000313|EMBL:OAJ63643.1, ECO:0000313|Proteomes:UP000078116};
RN   [1] {ECO:0000313|EMBL:OAJ63643.1, ECO:0000313|Proteomes:UP000078116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DCY85 {ECO:0000313|EMBL:OAJ63643.1,
RC   ECO:0000313|Proteomes:UP000078116};
RA   Dobritsa A.P., Kutumbaka K., Samadpour M.;
RT   "Reclassification of Paraburkholderia panaciterrae (Farh et al. 2015)
RT   Dobritsa & Samadpour 2016 as a later homotypic synonym of Paraburkholderia
RT   ginsengiterrae (Farh et al. 2015) Dobritsa & Samadpour 2016.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAJ63643.1}.
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DR   EMBL; LXKA01000121; OAJ63643.1; -; Genomic_DNA.
DR   RefSeq; WP_064268106.1; NZ_LXKA01000121.1.
DR   AlphaFoldDB; A0A1A9NBT1; -.
DR   STRING; 1462993.A6V36_29580; -.
DR   OrthoDB; 9803192at2; -.
DR   Proteomes; UP000078116; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          22..129
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          143..430
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   449 AA;  46790 MW;  E34F055F867F98AB CRC64;
     MAIKQTGDIA AQRLSPEQLS CEFSDIAPLL DASAAAAAAS RCHYCYDAPC VNACPTQIDI
     PSFIRKISNG NLKGAAVDIL SANPMGGMCA RVCPTEILCE GACVRNHQDA KPVAIGALQR
     HATDWAMARG EVLFTRAAPT GRRVAVVGAG PAGLACAHRL ALAGHDVTIY DAHEKAGGLN
     EYGIAAYKTV DDFAQREVEW LCSVGGIEIK HGVALGSDVD LDTLRKQYDA VFLAIGLTGV
     RALAMEGEDL SGVMNAVDFI EEVRSARDLG TVAVGRRVVV IGGGNTAVDA AVQSRKLGST
     SVTMVYRRGV ESMSATWAER EFAQTNGVTL VTHAKPHRLI GEGGVVTGVE FERTLGDGSQ
     ERFVVEADMV LKAIGQTLVP VGMERELLTV DGSRIAVDAN GQTSLAGVWA GGDCAATGGI
     DLTVQAVQDG KIAAAAIDAT FARTAVKAA
//