ID A0A1A9NJ91_9PROT Unreviewed; 374 AA.
AC A0A1A9NJ91;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Efflux transporter periplasmic adaptor subunit {ECO:0000313|EMBL:OAJ70108.1};
GN ORFNames=A7976_11945 {ECO:0000313|EMBL:OAJ70108.1};
OS Methylobacillus sp. MM3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylobacillus.
OX NCBI_TaxID=1848039 {ECO:0000313|EMBL:OAJ70108.1, ECO:0000313|Proteomes:UP000077549};
RN [1] {ECO:0000313|EMBL:OAJ70108.1, ECO:0000313|Proteomes:UP000077549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM2 {ECO:0000313|EMBL:OAJ70108.1,
RC ECO:0000313|Proteomes:UP000077549};
RA Macey M.C., Murrell J.C.;
RT "Draft genome of Methylobacillus sp. MM2 isolated from grassland soil.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAJ70108.1}.
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DR EMBL; LXTQ01000040; OAJ70108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A9NJ91; -.
DR STRING; 1848039.A7976_11945; -.
DR Proteomes; UP000077549; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000077549};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 41..275
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 276..343
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 93..151
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 374 AA; 39688 MW; 34FDB2F101A76B10 CRC64;
MTACNPSSGE NKAPPPKTAE VGVVEIASSA QPIVTELPGR TNARMIAEIR PQIGGIIQER
TFVEGAMVRA GQTLYRIDPA MYEAAYASAQ AALQKAEATY KSSKVKAERY TELVAINAVS
KQDYDDMQAT LKQSEADVAL AKAALETARI NLAYTRITAP ISGRVETSVV TPGALVTANQ
AAALTTVQQL DPIYVDVTQS SSDLLRLKRE LAKGNLKRIS ADEARIKVLL EDGSVYPHAG
RLSFSGVTVN PTSGAVTLRA IVPNPEGLLM PGMYVRAQLE EAVDEAAILV PQQSVTRTAK
GDALVLVVNA ENKVEQRRVE VGRAIGTQWL VNAGLAAGDR VIVEGVQQIR VGDAVKARVM
SAEAVDKSAE ASGK
//
