ID A0A1A9NLY8_9PROT Unreviewed; 953 AA.
AC A0A1A9NLY8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A7976_06675 {ECO:0000313|EMBL:OAJ71118.1};
OS Methylobacillus sp. MM3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylobacillus.
OX NCBI_TaxID=1848039 {ECO:0000313|EMBL:OAJ71118.1, ECO:0000313|Proteomes:UP000077549};
RN [1] {ECO:0000313|EMBL:OAJ71118.1, ECO:0000313|Proteomes:UP000077549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM2 {ECO:0000313|EMBL:OAJ71118.1,
RC ECO:0000313|Proteomes:UP000077549};
RA Macey M.C., Murrell J.C.;
RT "Draft genome of Methylobacillus sp. MM2 isolated from grassland soil.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAJ71118.1}.
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DR EMBL; LXTQ01000011; OAJ71118.1; -; Genomic_DNA.
DR RefSeq; WP_067108530.1; NZ_LXTQ01000011.1.
DR AlphaFoldDB; A0A1A9NLY8; -.
DR STRING; 1848039.A7976_06675; -.
DR OrthoDB; 8588402at2; -.
DR Proteomes; UP000077549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077549};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..257
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 262..306
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 351..403
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 406..445
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 473..525
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 557..690
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 699..953
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 953 AA; 107200 MW; 88A7A1B290D1CFD8 CRC64;
MTPPFFSRLR VQIPLAFVSL SAIVAILISV DHQRDTAERI VSENRDLLHI MMLQLDGMIA
NDTFEESMLQ GESRIPTTAL HTNMRRLLLV DEQNHVLQAS DSDWLGKTAS EISAFRPDLA
LLAQKRQRGE ILSNDNETLL YGYYPLPLGV QLSGTNSRQR WGTLFVEYDL GEPLAQARRH
AMNKAFRFLG LSLAAAILLG MLIDALVSRR TERLVSIASR IASGEMSARS GLVKPDEIGL
LGRAIDRMAD DLAADREALG RERKFSEDVI QSVTIPLFIL DKDHRVIIWN RACEMLTGIK
AIDIVGTTEA WRAFYSRPRP CLADLVLDGK SDHAGEYYQV VGSSVFNAHS FHAENWFSGL
NGQDRYLMFD ATPIYGNDGK LIAVIENLQD ITSIKKAEDH LRLTGQVIES TREAIVITDA
ENRIVSINRA FTDVTGYARE DVLGRDPSML ASGRHDKAFF HNMWESLHVR DSWQGELWNR
RKNGEVFPLW TNISSIRDNN GNLTHFVAIF ADISEHKATL KHIEFLAHHD TLTKLPNRLL
LLDRLQQAIN LAEREKHRVA LMFLDLDRFK QVNDSLGHHV GDDLLVAVVE RLKSCVRETD
TISRQGGDEF VIVLPDILDS NAATIIAEKI LETLREPFVI DGHQLSTSFS IGISLYPDDG
REIATLMQNA DTAMYHAKES GRNNCHYYDE SMNANAAERL KLQNKLRQAM EHGEFLLHFQ
PLISLKDHTI IGSEALLRWK SAEDGWVPPA KFIPLAEETG FILNIDAWVL REACRQAQEW
VNIGLPQLTV AVNISALQFK RGRILDSVNE ALAASGLAPH HLEIELTESV LIQDTQHTRK
QLNQLNSLGV RLSIDDYGTG YSNLSYLKQL DVDKLKIDQS FVKDMLVDEL DAIIVRSTVE
LAHNLGLQVL AEGVEDQAIL TLLQNLGCDQ AQGYHIGKPM PPKEFEKLLR SKL
//
