GenomeNet

Database: UniProt
Entry: A0A1A9T5G9_9PROT
LinkDB: A0A1A9T5G9_9PROT
Original site: A0A1A9T5G9_9PROT 
ID   A0A1A9T5G9_9PROT        Unreviewed;       360 AA.
AC   A0A1A9T5G9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   08-MAY-2019, entry version 12.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=A7981_07210 {ECO:0000313|EMBL:OAM53184.1};
OS   Methylovorus sp. MM2.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylovorus.
OX   NCBI_TaxID=1848038 {ECO:0000313|EMBL:OAM53184.1, ECO:0000313|Proteomes:UP000077545};
RN   [1] {ECO:0000313|Proteomes:UP000077545}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MM1 {ECO:0000313|Proteomes:UP000077545};
RA   Macey M.C., Murrell J.C.;
RT   "Draft genome of Methylovorus sp. MM1 isolated from grassland soil.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OAM53184.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; LXUF01000001; OAM53184.1; -; Genomic_DNA.
DR   RefSeq; WP_067266089.1; NZ_LXUF01000001.1.
DR   EnsemblBacteria; OAM53184; OAM53184; A7981_07210.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000077545; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077545};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077545};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       45    341       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   360 AA;  39051 MW;  FCC348DEADD63B16 CRC64;
     MSPYQKIATD DIRIKEIKEL APPSTLLEKL QASTATTDNI VAARSAIHGI LHSADDRLLV
     IVGPCSIHDP KSGIEYAKRL VTQRALFSKE LVIVMRVYFE KPRTTVGWKG LINDPHLDGS
     YKINEGLEIA RRFLLEVNEL GLPAATEFLD TITPQYTADL VSWGAIGART TESQIHRELA
     SGLSCPVGFK NGTDGNIKIA VDAIKAAASP HHFLSVTKEG HSAIVSTTGN EDCHVILRGG
     KTPNYDAASV EAAASELASA GLTAKVMVDC SHANSSRQYK MQTEVAKNVA DQLGNGDDRI
     IGVMVESHLY EGRQDHTPGC SLEYGKSITD ACLGWDDTLV VLETLAEGVR ARRRHEEVIE
//
DBGET integrated database retrieval system