ID A0A1A9US95_GLOAU Unreviewed; 285 AA.
AC A0A1A9US95;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Lipid droplet-associated hydrolase {ECO:0000256|ARBA:ARBA00019242};
DE AltName: Full=Lipid droplet-associated serine hydrolase {ECO:0000256|ARBA:ARBA00031924};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT013641-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT013641-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT013641-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. LDAH family.
CC {ECO:0000256|ARBA:ARBA00008300}.
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DR AlphaFoldDB; A0A1A9US95; -.
DR STRING; 7395.A0A1A9US95; -.
DR EnsemblMetazoa; GAUT013641-RA; GAUT013641-PA; GAUT013641.
DR VEuPathDB; VectorBase:GAUT013641; -.
DR OrthoDB; 5474978at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0019915; P:lipid storage; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR019363; LDAH.
DR PANTHER; PTHR13390; LIPASE; 1.
DR PANTHER; PTHR13390:SF0; LIPID DROPLET-ASSOCIATED HYDROLASE; 1.
DR Pfam; PF10230; LIDHydrolase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Lipid droplet {ECO:0000256|ARBA:ARBA00022677};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 285 AA; 32913 MW; 033261C8203A40BC CRC64;
MKEAFVNICN IPTHIITCGT WVEETLDNVK EVAICITGHL GHENPPETSL REVPQLKGNE
ELFDLDSQVR HKIEFIEKYV PEHTKIHLIG HSIGAWMVLQ ILRNESVHKR IKKCYLLFPT
IERMIESPNG WVFTKIALPL YSVFGFIISL LNRLPEILKI FLVQIYFWFA AIPNYLIGTA
LKYAKPSVVE KVVFLAEDEM ARVRALQRDI IKENMHLLKF YYGTTDGWVP IKYFTQLKEV
FPDIDADLDV KKIDHSFVLR YSKPMACIVG DFIIDNSEIL GMTTS
//
