ID A0A1A9USP9_GLOAU Unreviewed; 933 AA.
AC A0A1A9USP9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=GPI ethanolamine phosphate transferase 2 {ECO:0008006|Google:ProtNLM};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT014100-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT014100-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT014100-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A1A9USP9; -.
DR STRING; 7395.A0A1A9USP9; -.
DR EnsemblMetazoa; GAUT014100-RA; GAUT014100-PA; GAUT014100.
DR VEuPathDB; VectorBase:GAUT014100; -.
DR OrthoDB; 5479199at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR006124; Metalloenzyme.
DR InterPro; IPR039527; PIGG/GPI7.
DR InterPro; IPR045687; PIGG/GPI7_C.
DR PANTHER; PTHR23072:SF0; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2; 1.
DR PANTHER; PTHR23072; PHOSPHATIDYLINOSITOL GLYCAN-RELATED; 1.
DR Pfam; PF01676; Metalloenzyme; 1.
DR Pfam; PF19316; PIGO_PIGG; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 415..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 708..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..790
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 810..835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 869..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 908..929
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..258
FT /note="Metalloenzyme"
FT /evidence="ECO:0000259|Pfam:PF01676"
FT DOMAIN 772..912
FT /note="GPI ethanolamine phosphate transferase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19316"
SQ SEQUENCE 933 AA; 108046 MW; D1538FCCD3E354AB CRC64;
MDKANPSCFL FCMLTLFVSG SLLFFLGFFP ASQSQLVEIY GNGNVTTKPT QLDGVNLKVP
AGGPKQVILL VIDALRFDFV TASKMPYAYD HSCKFLSLKV DIPTVTMPRL KSIVTGAVSN
FIDIVLNLGH TTALKDSLLH RLRAKEKTAV FAGDRTWIEL FPREFSRYYE NIDSFFVYDF
FLGDSNITDT LKQEIQRNDW HFLILHYLGL DHIGHVEGSE SETISKKLLE MDSVIEYITK
NPKFENHLLL VTADHGMRNG GGHGGNEKEE VNVPIMLFQA NCLTKGKRPS LSQRNQIDLA
PTLAIILDID IPETSLSCLI PEFFESYTQE AQLYHLLYNA QHLMNKLTRK LSIDYIRQRA
YYQWWQEARN SHKHFLLSNI SSLVTFEKAK QNYMRFSKEV SRQLTQTLVE FEYDFIVIAL
TITTLSALTL LLNVLFENPL LCVMSKGFSL TVFLRCCFMA TVINYLCHYF NIISRSLLSG
ILLTLPVAFS LYLIWDLFQL ILQIILPLSP KFKAHFKLSI PSVLTTIFFI QIATRGSSSL
IEEEHWTWYY LTPTLLIFLT AQNFHNNIKH FWRNQKLREN MLLLRQTFEM RNAVFLLLII
VFCRYLNAND ARGYYTMDLA TIFRRKGNLF YLDLILLTGL GMLWWLLRKY NSPLQMFTCL
VTLLSVFGYR QSPKYPGIPL LIFWCGVLTT ACIHYSDICC KRGRSHSLGA TFNLLALLKT
NLTCCLLVSA LLHDPHNVIL LPALIFMLET SYQLCDNLYL KDKRLYNRSY ILILKTVLTI
FIANTFYFFQ GNTNKLSTIN INPGYIGLKS YNALLVGSLI TLNMYCAQIN AYLYLVWHMF
NTQVQTLPIR QEKEQITNMQ LFESTEEDLY LVLNLYTTTT VVPVAVYWWL LIAFRYHLFI
YSVYAPKAIY ECFQILVFYL NFIITTLYFK LFK
//
