ID   A0A1A9UUZ3_GLOAU        Unreviewed;       495 AA.
AC   A0A1A9UUZ3;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=PIGA GPI anchor biosynthesis domain-containing protein {ECO:0000259|Pfam:PF08288};
OS   Glossina austeni (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT016416-PA, ECO:0000313|Proteomes:UP000078200};
RN   [1] {ECO:0000313|Proteomes:UP000078200}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GAUT016416-PA}
RP   IDENTIFICATION.
RC   STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT016416-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A1A9UUZ3; -.
DR   STRING; 7395.A0A1A9UUZ3; -.
DR   EnsemblMetazoa; GAUT016416-RA; GAUT016416-PA; GAUT016416.
DR   VEuPathDB; VectorBase:GAUT016416; -.
DR   OrthoDB; 24420at2759; -.
DR   Proteomes; UP000078200; Unassembled WGS sequence.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR013234; PIGA_GPI_anchor_biosynthesis.
DR   PANTHER; PTHR45871; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN; 1.
DR   PANTHER; PTHR45871:SF1; PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A; 1.
DR   Pfam; PF13692; Glyco_trans_1_4; 1.
DR   Pfam; PF08288; PIGA; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          43..132
FT                   /note="PIGA GPI anchor biosynthesis"
FT                   /evidence="ECO:0000259|Pfam:PF08288"
SQ   SEQUENCE   495 AA;  56192 MW;  B7320153DE365CAA CRC64;
     MQRCKNIMVS DFFYPSIGGV EEHIFNLAQM LLKRGHKVII LTHCYNDCKG VRYLTNGLKV
     YYLPIKVFYN QSVLPTMICN VPLIRSVLLR EQIEIVHAHS AFSSLAHESI LIGSLLGLKT
     VFTDHSLFGF ADLSAVFTNK MLELDLGAVS HCICVSHVGK ENTVLRARVP KEKVSVIPNA
     VDTAFFIPDP SQRPNDGLIN IVLASRLVYR KGIDLSASII PRFKQMPHVK FIIVGDGPKR
     GLLEEIREKA NMQDRVEIVG AVEHARVRDY LVKGHIFVNT SLTEAYCMAI VEAAACGLQV
     VSTRVGGIPE VLPEDLIILT EPEVDSIYEG LLKALRRLNN CKYKRFANEV NRTSAPNGGG
     DEVRFPKTKH KSSRKRLNQR LSKRFNAINN FTVTKNTRNE FTSSDSESIL CPYKCNERVA
     SLYNWENITE RTEKVYNHIM LEPPSSLGSI LYSYLHGDVW PILLAISMVH LFLRFLEYIR
     PGRFMEKARE WPRRD
//