ID   A0A1A9V5N1_GLOAU        Unreviewed;       652 AA.
AC   A0A1A9V5N1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Protein krueppel {ECO:0008006|Google:ProtNLM};
OS   Glossina austeni (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT026791-PA, ECO:0000313|Proteomes:UP000078200};
RN   [1] {ECO:0000313|Proteomes:UP000078200}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GAUT026791-PA}
RP   IDENTIFICATION.
RC   STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT026791-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A1A9V5N1; -.
DR   STRING; 7395.A0A1A9V5N1; -.
DR   EnsemblMetazoa; GAUT026791-RA; GAUT026791-PA; GAUT026791.
DR   VEuPathDB; VectorBase:GAUT026791; -.
DR   OrthoDB; 3470185at2759; -.
DR   Proteomes; UP000078200; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1800.20; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 6.
DR   InterPro; IPR012934; Znf_AD.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR   PANTHER; PTHR24394:SF45; ZINC FINGER PROTEIN 771; 1.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 10.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS51915; ZAD; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          22..102
FT                   /note="ZAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51915"
FT   DOMAIN          325..352
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          397..424
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          427..455
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          455..482
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          483..510
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          538..565
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          566..594
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          202..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          245..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        245..265
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         24
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         27
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         75
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         78
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ   SEQUENCE   652 AA;  75671 MW;  8FF61F1EBB2A7499 CRC64;
     MQSPPGSPQS EKREAKAGEW QFWCRMCAKT DSRNNTNVLL NENPFRGGAN QEITLKEAIE
     RFFAVKEDVL PKVLCSYCFT LITTVTNYND RVWRVQRMFN DLISSFQDNY CDLDSVRLKF
     GICDESVPIS FSVPDLHCIA ENEIKKPVVN DEQEELLSDE NLEISSRFTR IKEEAIGDDV
     KRKKLEEALS IEECREVPFY EDSNGFKSSD EKEDPFSSAQ EDMDYNIGED VKNIKKLRSF
     SKHKHKKETD GEFDNHSENT EVGYAKTKKR RKKSQVKSKS NCQVKRHDIE LNIPCKECNQ
     MFDCFPTYRQ HLNTAHGLDD NLKDWKCPLC GKILTSASRL EQHVKSHLEI KRDFRTKTLN
     IKLDITCREC SEKFDCFEKY HQHLNSAHGQ VDKVKEWKCP SCEKVLTSVH RLEQHLRSHV
     PREPKMLPCS KCGAHFPTNG RLNAHIKNKH NTERFMCEEC GLCLSTSSNL KFHMLTHTDI
     APLECEVCKK RFKYARRLKI HMETHDSQKH ICNICGLQLN TRITLRRHMV VHNDIMKYKC
     DFCGRSFRQK KTLKYHLISH AGLKPYTCDL CDRAFTNGAN CRLHKQKIHP EEWAALEAAG
     RTKNIVQRLP NIETLKTLTR VAGNLTSLNS KQGANFRLDN SSRNPNDIVE KE
//