ID A0A1A9V6D2_GLOAU Unreviewed; 838 AA.
AC A0A1A9V6D2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Filamin-A {ECO:0008006|Google:ProtNLM};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT027426-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT027426-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT027426-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A1A9V6D2; -.
DR STRING; 7395.A0A1A9V6D2; -.
DR EnsemblMetazoa; GAUT027426-RA; GAUT027426-PA; GAUT027426.
DR VEuPathDB; VectorBase:GAUT027426; -.
DR OrthoDB; 298396at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537:SF18; FILAMIN-A; 1.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00630; Filamin; 9.
DR SMART; SM00557; IG_FLMN; 9.
DR SUPFAM; SSF81296; E set domains; 9.
DR PROSITE; PS50194; FILAMIN_REPEAT; 9.
PE 3: Inferred from homology;
FT REPEAT 1..51
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 51..143
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 141..231
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 234..326
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 324..424
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 435..519
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 521..614
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 616..707
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 744..838
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
SQ SEQUENCE 838 AA; 90617 MW; 3E9DF97FBBE62EE0 CRC64;
MPSGKVDKPV IQDNRDGTVS VKYEPKEEGI HELVVKYNGE PVQGSPFKFH VDSITSGYVT
AYGPGLTHGI TGEPCNFTIS TKGASAAGLT MAVEGPSKVD INYHDNKDGT VAVQYLPTAP
GEYHISVRFG DKHIKGSPYV AKVTGEGRKR NQISVGSCSE VTMPGVITDD DLRALNASIQ
APSGLEEPCF LKRMPTNNIG ISFTPREIGE HMVSVKRMGK HIPNSPFKVT VMEREVGDAK
KVKVSGVGLK EGKTHAENIF SVDTRNAGYG GLSVSIEGPS KAEIQCTDKD DGTLNISYKP
TEPGYYIVNL KFADHHVEGS PFTVKVTGEG SNRKREKIQR ERDAVPVTEI GSKCKLTFKM
PGITSFDLAA RVTSPSNVTE DAEIQEVEDG LYSVHFIPKE LGVHTVSVRY KDMHIPGSPF
QFTVGPLHDF GSHLVKAGGS GLERGVVGLP CEFNVWTREA GGGSLAISVE GPSKAEIEFK
DRKDGSCDVS YKVTEPGEYR VGLKFNDRHI PDSPFKVYIS PDAGDAHKLE VQQFPEGNIQ
ADAPYQFMVR KNGAKGELDA KIVAPSGTDD DCFIQAIDAE MYSIRFYPRE NGIHAIHVKF
NGVHIPGSPF RIKVGKDVAD PAAVSASGSG LETVKTGHKA DFIINTCNAG VGTLSVTIDG
PSKVAMDCTE VEEGYKVRYT PLLPGDHYVS VKYNNMHIVG SPFRVSCEGD KLADVGSQET
STVVVDTVAK FSKGGKNAGI HMPTFKSDAT QVTSKGMGLK KAFIGKQNTF TVNATDAGNN
ILYVGMYGPK GPCEEFTIKH TGRNNYNVSY SVRDRGQYIL IVKWGDENIP GSPFQIDV
//
