ID A0A1A9V7U5_GLOAU Unreviewed; 377 AA.
AC A0A1A9V7U5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Saccharopine dehydrogenase NADP binding domain-containing protein {ECO:0000259|Pfam:PF03435};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT028676-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT028676-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT028676-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00038048}.
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DR AlphaFoldDB; A0A1A9V7U5; -.
DR STRING; 7395.A0A1A9V7U5; -.
DR EnsemblMetazoa; GAUT028676-RA; GAUT028676-PA; GAUT028676.
DR VEuPathDB; VectorBase:GAUT028676; -.
DR OrthoDB; 3611694at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..138
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
SQ SEQUENCE 377 AA; 43166 MW; 21FB167CA8C703AC CRC64;
MSRNLDAIIF GASSYTGQFV IEEALEILKD FRWGIAGRNE KKLKRMLSDI EAKVKKDLSY
IPIIIADVND TNSLEIMAKQ CRIVLNCCGP YNILGEPVVK ACIDAGTHHV DITGEPQFIG
NMLLKYNDLA KEKGVYIVYA CGLESVPADL IYSFKYACEI LKLERQLNKE KLPPTKPKLW
LKPFPHQIET SHSYYCYFPA TDKFVIERSQ RYFYASQKKR PIQFQSYIGF RSFWLALLWP
FYVLLLLILS QFTWSRKALL RSPHLFSFGL VSAERPLESV QNTIEFAMTL KAKGWYREVP
HFIEPKKELV VRVTGKNPIY GVTSNAMLIC AKTILNENSK MPENGGVLSP ASAFAKTQII
EEIKRTKYGL KFDVIKT
//
