ID   A0A1A9VG17_GLOAU        Unreviewed;       613 AA.
AC   A0A1A9VG17;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Methionine--tRNA ligase, mitochondrial {ECO:0000256|ARBA:ARBA00026124};
DE            EC=6.1.1.10 {ECO:0000256|ARBA:ARBA00012838};
DE   AltName: Full=Mitochondrial methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030331};
OS   Glossina austeni (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT036036-PA, ECO:0000313|Proteomes:UP000078200};
RN   [1] {ECO:0000313|Proteomes:UP000078200}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GAUT036036-PA}
RP   IDENTIFICATION.
RC   STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT036036-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|RuleBase:RU363039}.
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DR   AlphaFoldDB; A0A1A9VG17; -.
DR   STRING; 7395.A0A1A9VG17; -.
DR   EnsemblMetazoa; GAUT036036-RA; GAUT036036-PA; GAUT036036.
DR   VEuPathDB; VectorBase:GAUT036036; -.
DR   OrthoDB; 166496at2759; -.
DR   Proteomes; UP000078200; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00814; MetRS_core; 1.
DR   Gene3D; 2.170.220.10; -; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014758; Met-tRNA_synth.
DR   InterPro; IPR023457; Met-tRNA_synth_2.
DR   InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR   InterPro; IPR033911; MetRS_core.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   NCBIfam; TIGR00398; metG; 1.
DR   PANTHER; PTHR43326:SF1; METHIONINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43326; METHIONYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF09334; tRNA-synt_1g; 1.
DR   PRINTS; PR01041; TRNASYNTHMET.
DR   SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363039};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363039};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363039}.
FT   DOMAIN          38..400
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   REGION          587..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   613 AA;  70870 MW;  596A282FC8953C82 CRC64;
     MPIFVQFKRN FNLIMLGQKV KLLKIALRTY SKKLAGNFYV TTPIFYVNGA PHIGHLYSAC
     LADAISRYQR LLCLENSGIT RLSTGTDEHG TKIDRAASAS KAPVMDYCTK MSHLFAEVFR
     EASVQHCDFI RTTEQRHEKA VHHFWNTLFE RDTIYLNQYN GWYCVADETF ITNNQLRLDE
     QSGARYSLES GHSVEWTEEE NYMFRLSKFQ ADILYWLQQG NRVRPVKFEK ILMDMLNEPL
     LDISISRPIN RVSWALPVPN DPTQTIYVWF DALVNYLTSV GYPDGKYTEF WAPNVQVIGK
     DILKFHGIYW PAFLIAAGME PPRQLYVHSH WTVDGQKMSK SKNNVIDPTI AAKTYTMEGL
     RYFLLREGTA HSDANYCSVK AMRILNAELA DTLGNLLSRV CSKALNPRQV YPRFHTAQLR
     EILKTNNGRQ LRDVLQQFEA KCTQHFNDGN FYMGADLIMS TLHAANRFLE FSRPWELKLK
     ISDVDIDKRL TLPMPQCDEN CLKLETIIAM TMDTLRVCGI ALQPLVPSLS TLLLDKLRVP
     YDQRKWRNLN HHFVQVAEGA LEPPLEVCLN RTHLILFRRL TPKEDDHVEP KLAKMKEPEK
     CKKSKRKTKN VVS
//