ID A0A1A9VJX6_GLOAU Unreviewed; 823 AA.
AC A0A1A9VJX6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=ATP synthase subunit alpha, mitochondrial {ECO:0000256|ARBA:ARBA00016087};
DE AltName: Full=39S ribosomal protein L17, mitochondrial {ECO:0000256|ARBA:ARBA00035413};
DE AltName: Full=Large ribosomal subunit protein bL17m {ECO:0000256|ARBA:ARBA00035290};
DE AltName: Full=Transcript cleavage factor GreA {ECO:0000256|ARBA:ARBA00030776};
DE AltName: Full=Transcription elongation factor GreA {ECO:0000256|ARBA:ARBA00013729};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT039565-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT039565-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT039565-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family.
CC {ECO:0000256|ARBA:ARBA00008936}.
CC -!- SIMILARITY: Belongs to the GreA/GreB family.
CC {ECO:0000256|ARBA:ARBA00008213}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL17 family.
CC {ECO:0000256|RuleBase:RU000660}.
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DR AlphaFoldDB; A0A1A9VJX6; -.
DR STRING; 7395.A0A1A9VJX6; -.
DR EnsemblMetazoa; GAUT039565-RA; GAUT039565-PA; GAUT039565.
DR VEuPathDB; VectorBase:GAUT039565; -.
DR OrthoDB; 3612036at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd18113; ATP-synt_F1_alpha_C; 1.
DR CDD; cd18116; ATP-synt_F1_alpha_N; 1.
DR CDD; cd01132; F1-ATPase_alpha_CD; 1.
DR Gene3D; 2.40.30.20; -; 1.
DR Gene3D; 1.20.150.20; ATP synthase alpha/beta chain, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.90.1030.10; Ribosomal protein L17; 1.
DR Gene3D; 3.10.50.30; Transcription elongation factor, GreA/GreB, C-terminal domain; 1.
DR Gene3D; 1.10.287.180; Transcription elongation factor, GreA/GreB, N-terminal domain; 1.
DR HAMAP; MF_01346; ATP_synth_alpha_bact; 1.
DR HAMAP; MF_00105; GreA_GreB; 1.
DR HAMAP; MF_01368; Ribosomal_L17; 1.
DR InterPro; IPR023366; ATP_synth_asu-like_sf.
DR InterPro; IPR000793; ATP_synth_asu_C.
DR InterPro; IPR038376; ATP_synth_asu_C_sf.
DR InterPro; IPR033732; ATP_synth_F1_a_nt-bd_dom.
DR InterPro; IPR005294; ATP_synth_F1_asu.
DR InterPro; IPR020003; ATPase_a/bsu_AS.
DR InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR InterPro; IPR036121; ATPase_F1/V1/A1_a/bsu_N_sf.
DR InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR InterPro; IPR036953; GreA/GreB_C_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000456; Ribosomal_bL17.
DR InterPro; IPR036373; Ribosomal_bL17_sf.
DR InterPro; IPR018151; TF_GreA/GreB_CS.
DR InterPro; IPR006359; Tscrpt_elong_fac_GreA.
DR InterPro; IPR028624; Tscrpt_elong_fac_GreA/B.
DR InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N.
DR InterPro; IPR036805; Tscrpt_elong_fac_GreA/B_N_sf.
DR NCBIfam; TIGR00962; atpA; 1.
DR NCBIfam; TIGR01462; greA; 1.
DR NCBIfam; TIGR00059; L17; 1.
DR PANTHER; PTHR48082; ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48082:SF2; ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00006; ATP-synt_ab; 1.
DR Pfam; PF00306; ATP-synt_ab_C; 1.
DR Pfam; PF02874; ATP-synt_ab_N; 1.
DR Pfam; PF01272; GreA_GreB; 1.
DR Pfam; PF03449; GreA_GreB_N; 1.
DR Pfam; PF01196; Ribosomal_L17; 1.
DR SUPFAM; SSF47917; C-terminal domain of alpha and beta subunits of F1 ATP synthase; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF46557; GreA transcript cleavage protein, N-terminal domain; 1.
DR SUPFAM; SSF50615; N-terminal domain of alpha and beta subunits of F1 ATP synthase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF64263; Prokaryotic ribosomal protein L17; 1.
DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
DR PROSITE; PS00829; GREAB_1; 1.
DR PROSITE; PS00830; GREAB_2; 1.
PE 3: Inferred from homology;
KW ATP synthesis {ECO:0000256|ARBA:ARBA00023310};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW CF(1) {ECO:0000256|ARBA:ARBA00023196}; Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Ribonucleoprotein {ECO:0000256|RuleBase:RU000660};
KW Ribosomal protein {ECO:0000256|RuleBase:RU000660};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 196..261
FT /note="ATPase F1/V1/A1 complex alpha/beta subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02874"
FT DOMAIN 318..541
FT /note="ATPase F1/V1/A1 complex alpha/beta subunit
FT nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF00006"
FT DOMAIN 548..653
FT /note="ATP synthase alpha subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00306"
FT DOMAIN 669..737
FT /note="Transcription elongation factor GreA/GreB N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF03449"
FT DOMAIN 745..821
FT /note="Transcription elongation factor GreA/GreB C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01272"
FT COILED 675..702
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 823 AA; 91404 MW; FDF8AA185DAF51DD CRC64;
MKHGIKKRKL SRCTEHRLST LKNLSISLIN HEQIVTTLPK AKELRPYVEK FITIAKNKNT
LHGRRLLLSR LHNSKLAVDK LLNVLASRYQ DRKGGYSRII KFSTRKGDCA SMAVIELVNR
DIAAREKFLS LAKENENEFE ITIKSAEALK ESDIKIITES LSFLGKIIKN SMNVSEIASV
IREKVETFDN PIKRENIGEV ISVTDGIALV YGLEKAKFGE KVFFASGVEG IVLDLDHDTA
GIVVLGNDRD VKEGDVVKCS GDVVQVPIGH ELLGRVVNAL GHPIDDGGEI RAKNRMDIES
KAPGIIDRKS VHEPLQTGIK IIDLLIPIGR GQRELIIGDR QIGKTTIALD TIINQKKIND
EVNENQKIYC VYVAIGQKIS TVAKVVNKLK ESGALEYTTV VVASASDCAP MQFLAPYAGC
TIGEFFRDNG MHCLIIYDDL SKHAVAYRQM SLLLRRPPGR EAYPGDIFYV HSRLLERAAK
MSDKKGQGSL TALPIVETQA GDVSAYVPTN VISITDGQIF LESELFYKGF RPAVNIGLSV
SRVGSAAQLK SVKKVASSIK LSLAQYRELE DFAKFGSDLD ASVQLSLNKG KYLVELLKQK
QHLPMSIEEQ LSKIQISYIN KFEHDLINYF HTVHPGVLKK LSNDMSNDIK GDIFNIVVIM
ASSIINKFPM TREGFENMQA ELEKLKEEKP SVIQAISDAR DQGDLSENAE YHTARERLGF
IEGRIMEIES KLSHAEVIEV KNLSGDSVMF GATVTLSMLS DDDSEVEYTY KVVGEYEADV
SKRLISTSSP LGSALIGKKV GEYVEVTVPN GEKLYKIVKI EFK
//
