ID   A0A1A9VQJ1_GLOAU        Unreviewed;       515 AA.
AC   A0A1A9VQJ1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   13-SEP-2023, entry version 29.
DE   RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
OS   Glossina austeni (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT044426-PA, ECO:0000313|Proteomes:UP000078200};
RN   [1] {ECO:0000313|Proteomes:UP000078200}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GAUT044426-PA}
RP   IDENTIFICATION.
RC   STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT044426-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC       transporter (TC 2.A.1.1) family. {ECO:0000256|RuleBase:RU003346}.
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DR   AlphaFoldDB; A0A1A9VQJ1; -.
DR   STRING; 7395.A0A1A9VQJ1; -.
DR   EnsemblMetazoa; GAUT044426-RA; GAUT044426-PA; GAUT044426.
DR   VEuPathDB; VectorBase:GAUT044426; -.
DR   OrthoDB; 1899001at2759; -.
DR   Proteomes; UP000078200; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd17357; MFS_GLUT_Class1_2_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR045263; GLUT.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR003663; Sugar/inositol_transpt.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   NCBIfam; TIGR00879; SP; 1.
DR   PANTHER; PTHR23503:SF127; FI08437P-RELATED; 1.
DR   PANTHER; PTHR23503; SOLUTE CARRIER FAMILY 2; 1.
DR   Pfam; PF00083; Sugar_tr; 1.
DR   PRINTS; PR00171; SUGRTRNSPORT.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003346}.
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        222..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        403..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        467..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          51..495
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   515 AA;  56596 MW;  D6C4128B2064D390 CRC64;
     MELRNLEESQ HLYPQLTKGE VIISNGGDRG PPKIRDCLKK PQWGKLLTLV GYASTIGSAV
     PVGYCIGVIN SPATLIKSWC NDVINERYNV QLRASNLEIL WASIVSVFLI GGAIGSLGGA
     WVANKFGRKG CFLISGLLFM IGGIMFSFCR MANSVEMLIL GRLLVGLASG LTTATLPMYL
     TEIAPLALRG ALGVFCAVGV TGGVVVGQVF SLRNIFGTSD LWHYALSFYM VLVVICYLPS
     YYFPESPKYL YIVLGDRERA LRELLRLRGT DALVLIQHEM EEMDMEINTK IVTSSFFSVL
     RDPALMLPLI IVCCFHGGQQ FSGINAIFYY SVSIFEKAGL STTDAEWANL GAGCLNLATS
     FLGPVLMAKV NRRPLMMFSS AVCACFLFTI AFILYYIEAF SWLPMACIVC VMGYIFFYQF
     GLGPIPYFIG AELFEVAPRP VAMSMGSLAS WSCNFVIGMA FPSLSRAWGA FVFLPFSLTC
     ALLFLLTKFY LPETRGRDPS EVAPLVAKGF RSKVT
//