ID A0A1A9VQV4_GLOAU Unreviewed; 570 AA.
AC A0A1A9VQV4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE RecName: Full=Big brain {ECO:0008006|Google:ProtNLM};
OS Glossina austeni (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7395 {ECO:0000313|EnsemblMetazoa:GAUT044714-PA, ECO:0000313|Proteomes:UP000078200};
RN [1] {ECO:0000313|Proteomes:UP000078200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTRI {ECO:0000313|Proteomes:UP000078200};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GAUT044714-PA}
RP IDENTIFICATION.
RC STRAIN=TTRI {ECO:0000313|EnsemblMetazoa:GAUT044714-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A1A9VQV4; -.
DR STRING; 7395.A0A1A9VQV4; -.
DR EnsemblMetazoa; GAUT044714-RA; GAUT044714-PA; GAUT044714.
DR VEuPathDB; VectorBase:GAUT044714; -.
DR OrthoDB; 3236018at2759; -.
DR Proteomes; UP000078200; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR PANTHER; PTHR19139; AQUAPORIN TRANSPORTER; 1.
DR PANTHER; PTHR19139:SF268; NEUROGENIC PROTEIN BIG BRAIN; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..496
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 63742 MW; 132AEBF6300EFBDD CRC64;
MESVSQYATK TRSANNNAPN MLSMKRHNIY LRNIILRNSS VSTRAKTMHQ EAIFFHELAE
VAKSSDIFGV TVPGYQGNLQ AAISHNASLA AWERLGVEFI LTFVVVLTYF ISTDSVKKVM
GNSAPSIAAS YSACSFVSMP YLNPARSLGP SFVLNKWENH WVYWFGPLIG GFASGLVYEY
IFNTRRNSRR IKVNMENDSS SINSEDDLNY DLDMEKSNMH SKFQGTYQRA QATNGHGQSN
TNSGKSNGGN YCQNLYTTPP LLNKFEQAEP LYGGTRSMYC RSPTLTRTNL NRSQSVYAKS
NTALNRDIVP RSGPLVPAQS LYPLRLGFSQ HRAQSSHLQN QNVQNQLQQR SESIYAIRSL
RQNQLQQQQQ QQQHSTQIKQ QQQQQRHQQP QQAAEHMQQS QPVATQRGQT AQENQACFQA
VYGTRLNPNP NDGHLKFDRR PETVYGVTMP GNRGQSAQSD DSSYGSYPSS SVTPPARTEP
PTVLLYAPPP NPNSATTPPL RTQSERKVSA PVVVSQASTI SMGQYSANQS SNANQTGSVQ
NQPQQQQIIM QHAQQSHQHQ HYAIMPLRSN
//
