ID   A0A1A9W4B8_9MUSC        Unreviewed;       661 AA.
AC   A0A1A9W4B8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:GBRI005820-PA};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI005820-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI005820-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI005820-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004439}. Early endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004520}. Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A1A9W4B8; -.
DR   STRING; 37001.A0A1A9W4B8; -.
DR   EnsemblMetazoa; GBRI005820-RA; GBRI005820-PA; GBRI005820.
DR   VEuPathDB; VectorBase:GBRI005820; -.
DR   OrthoDB; 1342875at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16698; RING_CH-C4HC3_MARCH1-like; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR011016; Znf_RING-CH.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR45981; LD02310P; 1.
DR   PANTHER; PTHR45981:SF3; LD02310P; 1.
DR   Pfam; PF12906; RINGv; 1.
DR   SMART; SM00744; RINGv; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS51292; ZF_RING_CH; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   TRANSMEM        124..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          37..98
FT                   /note="RING-CH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51292"
FT   DOMAIN          45..92
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
SQ   SEQUENCE   661 AA;  73323 MW;  98193AC3416D9DA4 CRC64;
     MPCDNTTKTS SDIEHADWTT GTNQHYNVRF DSASSQASQS SGDICRICHC ESDPQNPLLT
     PCYCSGSLKY VHQACLQQWL TASETNACEL CKFPFIMHTK IKPFNEWRSL DISGIERRRL
     CCSVLFHCAA ALCVIWSLCV LIERAADDVK NGQIDWPFWT KLAVVAVGLT GGIVFMYIQC
     KAYLHLCHRW KARNRILLIQ NAPEKVHPLS QPSPLAQQRV RHSSTVQAHT TNASHRSVNV
     NIDVNNGSAR PPTSVTDYAP AALADVDDLS GSCVRHQRYE NLPSSPHHML QHADLDVDSV
     AYHNTAGVPR SHGKHHYLHH QNIGHGHHIN GHQHQHSHYH TQLGQVAVAA NIECSQSQNN
     YERDFALDDV VSQISSFRPC PQGSGSMTPF HDSIHNVLEH SEDSSRVSVN DLCVGSRQDL
     SADGLSSDTG REHALQLSSF SGSGDHKAPS ISSGVSHAVA NGLGGFVYKP HTKRYSNSSI
     FLENRDILND SVAMDLDLDS TSYIKPDYRH SSILTPPESE SDKFEQYVGK DLRRYSDTKL
     LGNLDSDARN STLECKNEFE NDSTTANSHM HPLLKQHSDT ATALNTKDVM LDATLPISPL
     SSSRMQQLER PLLWHSIQTV NVGRGGENVA TPSAQQQIEK ARFFFKSLPN LSSSCESLIK
     K
//