ID A0A1A9WAR2_9MUSC Unreviewed; 973 AA.
AC A0A1A9WAR2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
OS Glossina brevipalpis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI012466-PA, ECO:0000313|Proteomes:UP000091820};
RN [1] {ECO:0000313|Proteomes:UP000091820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GBRI012466-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI012466-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663}.
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DR AlphaFoldDB; A0A1A9WAR2; -.
DR EnsemblMetazoa; GBRI012466-RA; GBRI012466-PA; GBRI012466.
DR VEuPathDB; VectorBase:GBRI012466; -.
DR OrthoDB; 4549343at2759; -.
DR Proteomes; UP000091820; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24238; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24238:SF57; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..412
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 856..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..871
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..962
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 973 AA; 109165 MW; 56B06DCC589E4D5F CRC64;
MAQQTMEQYH HSQHEDDDDI NIAASTSNLA DIEAKLKESP DKYLYYIAEF LAGHINETKG
IVAHFNGPIL KSSIKSVFWL FLLQYAVLAM LGIVMNIAII GCCLYHRFYR DVTQAFIINL
ALCHFVQCAV VLPITLMVMM IQNWIFGQFL CFFLPMLQDI PLHVAMITHI LIAWDRMRWL
SDPLKCRFPA FVCCCATWLT GMIIALPYPI YTIYLEMGKF VPSLHGVGLC ILNLMDDMHE
YMRGLFFLMY CAPAVLLAYI YIRTSQELRP PDGPLSEYRA VVRMRQRNSS ASSVERSYSN
ATTATVGGSA IAGAAAGTNV GIGHHYTYST GTATRSYDLY HAELDVYHEK RNQRNFGSMA
ATQVICVCPL MILRFARLSI EETYANQKHF DFTYLMFVWI AFLPTVIFPI IYAIQLLPRT
EQERIRGYFR LLTKHLPKES NKTLVDVNTP SSHENSVEKD ENTNISQRTS IVLNGDGYID
ATVGGDSTAR ITLKKNMNEL KPPKRQMRND VNDVKNESKD NLSKQDYEGV KKINERMKDG
FGSNANNLSD VLSYKREKEP TQLLPHSNDL NVNIISSVNS TSPAVQRHNK TNTSRCSGAF
AVNQRKLETL DNRSSMTSST YCNGNSSLVD EDDLSNFGDG ENSSIVSGMV VQIGSQGSSI
GLPPYHEGKM SSYAEVLKTH DISSSDISYN LSRMNSSSTF ENELDTIDLL ERERNSMDMQ
VLLDKEEKNM RERRRLPDIG KLCNRSPKFR SKATSTTTLS AKIPVTSDPL QMSSETFGTS
STLNVESSSI SSHIMQLDND KFDLSSRSAI INEHSIDEEI PGDFYDTYKP GDAKLVPPES
VLPVSSPIQY QYTRRLSRKT SHHQHHGSNI SSHRLSKRDS FHAMHSNDLI AGAFGELDPT
QPLTKMSIID NRMLMRRSSG NSGVGGGNGG SGSRASAFSS SSRSSMKSRD YNHGSTHSPQ
PELDFRENIF AEL
//
