ID A0A1A9WC14_9MUSC Unreviewed; 608 AA.
AC A0A1A9WC14;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
OS Glossina brevipalpis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI013998-PA, ECO:0000313|Proteomes:UP000091820};
RN [1] {ECO:0000313|Proteomes:UP000091820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GBRI013998-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI013998-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the synaptotagmin family.
CC {ECO:0000256|ARBA:ARBA00006996}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A1A9WC14; -.
DR STRING; 37001.A0A1A9WC14; -.
DR EnsemblMetazoa; GBRI013998-RA; GBRI013998-PA; GBRI013998.
DR VEuPathDB; VectorBase:GBRI013998; -.
DR OrthoDB; 2875354at2759; -.
DR Proteomes; UP000091820; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd08389; C2A_Synaptotagmin-14_16; 1.
DR CDD; cd08408; C2B_Synaptotagmin-14_16; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR043541; SYT14/14L/16.
DR PANTHER; PTHR46129; SYNAPTOTAGMIN 14, ISOFORM D; 1.
DR PANTHER; PTHR46129:SF2; SYNAPTOTAGMIN 14, ISOFORM D; 1.
DR Pfam; PF00168; C2; 2.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 312..431
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 467..603
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 207..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 68138 MW; 74A077F1ED12006C CRC64;
MIVTSGVDNY VLNGTVEITT VLSALFGVIA LMLLIFLYVH RKWCFHARRG LHCCDDKYLA
SKCVQKLCKC FDIKCFPYLW IIVLIYFIIF LARKRRYENT SSDSEEDILR RLRLQQARLT
SPHGGGTSAG QYTNYGINQV NPLSQHFTYA NSDLQRVTVA PRDFPRDPLA IAERGKVGIP
SSHSECSSND SVEASFDSHS GILIGEKKER HHSSVSNATE ANISSSSSLK ETHIEANVDP
DPPKSSKYQK ICDVNARTTT PPRQDSLEDD NSIIASNNSN NNFNEDEPLF DTSDLRSLKS
DDISMQTQCY GKSGSIEISL LYDAPLRKMT VHVLQARGLP ILGNGQQTHT QVRLLMLPNK
KQKHKTKIRS GENPQYLESF LLHRVTPEEV NNMGLRVRLY GCERLRKERL IGEAYVSFAT
IDLELETNLW LPLEPRNTSS VLGSSSDLLS LARSDSAGST TSMQHGGVPE LLLSLGYNGT
TGRLTVEIVK GSYFRNLSQN KAPDTYVKLC LVSSIGQEIS RAKTSTRRAQ PNPLFKETFV
FQVALFQLND VTLMVSVYAK RNMKKNEMVG WFSLGLNSSG PEEVAHWVDM RDMAKGELLA
RWHVLVDS
//
