ID   A0A1A9WD09_9MUSC        Unreviewed;       575 AA.
AC   A0A1A9WD09;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Pickpocket protein 28 {ECO:0008006|Google:ProtNLM};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI015067-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI015067-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI015067-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A1A9WD09; -.
DR   STRING; 37001.A0A1A9WD09; -.
DR   EnsemblMetazoa; GBRI015067-RA; GBRI015067-PA; GBRI015067.
DR   VEuPathDB; VectorBase:GBRI015067; -.
DR   OrthoDB; 3414706at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        95..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        530..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   575 AA;  65953 MW;  FC52E06B82E50E61 CRC64;
     MEGNDEKKWD TRPSQNSLQA PLQWKRAALM TKTITAFKET ISVDSDNDDV DTKQQIKYGK
     PSQAAWAIVS EYCDNSTIHG MKYLGEHKRP WWERIFWIMV FGFSIYTCAA LIMNIWYKWN
     YNPVIVSFAE KSTPVWEIPF PTITVCPENK APQTIFNYTD TFWKLKDFYS NITQEYPTRE
     SLAYFYVVSQ VCDLHIIQQS KPDADFVQGI EIIGRLSEIM PAFNETFLRC KWRNSLQNCA
     NLFHKFITDD GICYSFNSLS VEEIYRQEGL IPDLMLHFEN RTRTDWNVED GYSFSTQTST
     YPKRVLGPGT KAGLDLLLNG YEKDFDNLCR GPVQGFKILL QTPGELPLMS KRFFRIPFDQ
     EILISIKPKI ITTSSGLKHY EPNNQNNCEL ECLANFTLSK CGCVKYSMPR RYAAPVCGPK
     KISCLYDAED KLALEEFNQG VSATDSSYRA PTTCNCLPAC TSIAYEAEIS QADYDYKSLT
     GLKGTSNPKD ELYGAKKSRL SIFFKEAQFL TSKRSELYGT TEFLANCGGL LGLFMGVSTL
     SIVEILYFCT VRLATNLRMR HKKRKEIQNY EDKTA
//