ID   A0A1A9WH38_9MUSC        Unreviewed;       860 AA.
AC   A0A1A9WH38;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI019480-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI019480-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI019480-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A1A9WH38; -.
DR   STRING; 37001.A0A1A9WH38; -.
DR   EnsemblMetazoa; GBRI019480-RA; GBRI019480-PA; GBRI019480.
DR   VEuPathDB; VectorBase:GBRI019480; -.
DR   OrthoDB; 7959at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd07595; BAR_RhoGAP_Rich-like; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR   PANTHER; PTHR14130:SF14; RHO GTPASE-ACTIVATING PROTEIN 92B; 1.
DR   Pfam; PF03114; BAR; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          250..445
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          464..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          664..713
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          834..860
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..488
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        507..599
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..678
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        693..713
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   860 AA;  96764 MW;  800EBEBB621A0D0A CRC64;
     MKKQFTKMMI AAENLSRSTK QDRKDFELEN VEKQVEKYRD VLEKMVRKLP AVSVSGSTVI
     DNQERDKRIK KQSHYKIGIA LEESSKELSK DMPLHHVLVN CGELEKSIAE CIVDSELETE
     TEVVRRLKLI LDNEIQDIST LKRNVSRTVQ EYTSLKRSYE AAIRLDESQS KINHIKDQQE
     QCEVKLDKER DAWAAQMFEL IAKEDDIVQC VRDYILNQRN YHERALKKIN SSLTSIQDII
     QSTVKSRFGT SLDEHLVSTN REISQIIELC VCCLVENGLC EEGLLRVGCA STKLRRMKHA
     LEAQYVKTPL PIDYQDPHVI ACILKLYLRE LPEPLLTHTY YKDFIKAVEP HTDAERKAEI
     KRILEKLPTE NYKNLRYLTK FLWLITQYVG ENKMSSQNLA IVMSPNMLWP PVDKNNPADY
     MGQVNCSSAV NVIVELLISQ WDYFFDGDVD FFVTLQRGKI YMEDKSKSSS SNENLDRSEN
     DAAESPRYGT IRRQKPCAPS PPTKLHNLLN PEMNGQSTVM VDPNNKQNNT DIQQMQQQQQ
     PQQQQQTNHQ RTKELFPGNN NGSNCQSSGS SLIVNNNNNN SNTNHNNNNN NNSSQIEKPE
     KLSLSKQLML MPAESLINIT TTTSVGAVTA TVTSTATTAA VVHKPIPMTR TQFLCMDNLT
     SPVADRKSTD SVNSLTFKPD LPQKPKIPKR PITLGLTNTS TNTANSNKSD EENLELSSGA
     VAAMGGSFRG HKTAVQLVQE HCDNITALQA NIGTSNTSTA PLILVRETNH NNQQQQQQQA
     NEVNANAQLI NKSSQIITNP PLTLATTSQP LTTNEKTPIA TETTIRITPT TPVTPNIIIA
     PKRPTVPAPP PPVLIKKQAD
//