ID   A0A1A9WJH1_9MUSC        Unreviewed;       604 AA.
AC   A0A1A9WJH1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=NR LBD domain-containing protein {ECO:0000259|PROSITE:PS51843};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI022019-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI022019-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI022019-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A1A9WJH1; -.
DR   STRING; 37001.A0A1A9WJH1; -.
DR   EnsemblMetazoa; GBRI022019-RA; GBRI022019-PA; GBRI022019.
DR   VEuPathDB; VectorBase:GBRI022019; -.
DR   OrthoDB; 5400963at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1.
DR   PANTHER; PTHR24083:SF185; STEROID RECEPTOR SEVEN-UP, ISOFORM A; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   PRINTS; PR01282; COUPTNFACTOR.
DR   PRINTS; PR00398; STRDHORMONER.
DR   SMART; SM00430; HOLI; 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          43..269
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          214..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          377..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   604 AA;  64332 MW;  8E2C10068C96BC88 CRC64;
     MHGLAVQRGR VPPTQPGLAG MHGQYQLANG DPMGVAGFNG HSYLSSYISL LLRAEPYPTS
     RYGQCMQPNN IMGIDNICEL AARLLFSAVE WAKNIPFFPE LQVTDQVALL RLVWSELFVL
     NASQCSMPLH VAPLLAAAGL HASPMAADRV VAFMDHIRIF QEQVEKLKAL HVDSAEYSCL
     KAIVLFTTGK LLDILFKDVP ALLTKISMKV SAVSGSGNSA TTTTTNTNAS HNSSDSSERS
     SEGSDDIMLL VKEHLEEFNR LEVEQQQQQF SAAALHLATF MKTVAGVETV TQIRSGNSSK
     DNFHPTTVST SSGAAATAAA TVASSSRISV NTTAGGIVHS ATSAFSSCAP SHTKNVNQDD
     LLTALYNSAN NGVNHNLTNN SSGLGNSVNS QTLNGSDSPI HSSNHAIISS SSSNTNTIMA
     NPSYPSPSTS SAQQSQVQHQ QQQQAAAAAA AMFYQTPPRA AFGSAFDMFH HSTPFGVSHA
     AAAAAAAAHS GSGASFGSPS YRYSPYSFGN VMLRFSELSI PYATYDVYIL TDLLSGANVT
     HAGTKLFLSC VNFKALLLGT IAKLLNNGSC SLAITLTVKH TVTSNEHYHQ QQQQQEQQQH
     QRDT
//